4-Chloro-2,6-diaminopyrimidine

Product Name:4-Chloro-2
6-diaminopyrimidine
CAS:156-83-2
MFC4H5ClN4
MW:144.56
EINECS:205-863-9
MOL File:156-83-2.mol

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1. Chemical Profile & Specifications

Parameter 4-Chloro-2,6-diaminopyrimidine Generic Pyrimidine Derivatives
CAS No. 156-83-2 Varies
Molecular Formula C4H5ClN4 Typically C4-6H4-8N2-4X
Molecular Weight 144.56 g/mol 120-180 g/mol
Structural Features Chlorine at C4, amino groups at C2/C6 Variable substituents
Purity Grades Pharma (≥98%), Technical (≥95%) Typically 90-99%

2. Key Applications in Pharmaceutical & Chemical Industries

Core Applications:

  • Hypertension Drug Synthesis: Critical intermediate for Minoxidil API production
  • Anticancer Research: Backbone for kinase inhibitor development
  • Agrochemicals: Precursor for herbicidal compounds
  • Coordination Chemistry: Ligand in metal-organic frameworks (MOFs)

3. Industrial Use Cases

Case 1: Pharmaceutical Intermediate Production
Used in continuous flow synthesis systems for high-purity Minoxidil precursors under GMP conditions.

Case 2: Specialty Chemical Manufacturing
Serves as key building block in heterocyclic compound libraries for high-throughput screening.

4. Client Success Stories

Client A: Top-10 Global Pharma Company
– Requirement: 500kg annual supply of GMP-grade material
– Solution: Customized crystallization process achieving 99.7% purity
– Outcome: 30% yield improvement vs previous supplier

Client B: European Research Consortium
– Requirement: Isotope-labeled derivatives for metabolic studies
– Solution: 13C/15N labeled compounds with 98% isotopic enrichment
– Outcome: Enabled breakthrough ADME research publication

5. Technical Inquiry & Custom Solutions

For bulk pricing, regulatory documentation (CoA, MSDS), or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826

Technical teams available 24/7 for formulation support and regulatory compliance consulting.

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