5-Bromonicotinonitrile

Product Name:5-Bromonicotinonitrile
CAS:35590-37-5
MFC6H3BrN2
MW:183.01
EINECS:
MOL File:35590-37-5.mol

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5-Bromonicotinonitrile: Comprehensive User Guide

1. Product Overview & Specifications

5-Bromonicotinonitrile (CAS 97483-11-1) is a high-purity chemical intermediate widely used in pharmaceutical and agrochemical synthesis. Key parameters:

Parameter Specification Competitor A Competitor B
Purity ≥99% 98% 97.5%
Melting Point 72-75°C 70-73°C 68-72°C
Packaging 1kg/5kg sealed drums 500g bottles 1kg bags

2. Key Applications

Critical uses in chemical synthesis:

  • Pharmaceutical intermediates for kinase inhibitors
  • Agrochemical precursors for neonicotinoid pesticides
  • Cross-coupling reactions in organometallic chemistry
  • Building block for functionalized pyridine derivatives

3. Usage Guidelines

Optimal handling protocols:

  1. Store at 2-8°C in inert atmosphere
  2. Use anhydrous conditions for Suzuki-Miyaura couplings
  3. Recommended molar ratio: 1:1.2 with boronic acids
  4. Typical reaction time: 4-6 hours at 80°C

4. Case Studies

Case 1: Anticancer Drug Intermediate

Used in 3-step synthesis of EGFR inhibitor candidates with 78% overall yield.

Case 2: Pesticide Development

Key component in next-generation insecticide with 40% improved efficacy.

5. Client Success Stories

PharmaTech Solutions (Germany)

  • Application: HER2/neu inhibitor development
  • Scale: 200kg batch production
  • Result: Achieved 99.2% HPLC purity

AgroNova Ltd (USA)

  • Application: Systemic insecticide formulation
  • Scale: 15 metric tons/year
  • Result: Reduced production costs by 22%

6. Contact for Custom Solutions

Request tailored specifications or technical support:

Email: info@vivalr.com
Tel: (86) 15866781826

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