Comprehensive Guide to 4-Chlorothieno[3,2-d]pyrimidine
Table of Contents
1. Product Overview & Specifications
4-Chlorothieno[3,2-d]pyrimidine (CAS 5390-89-4) is a heterocyclic compound with molecular formula C6H3ClN2S. Key parameters:
| Parameter | Specification | Comparison vs. Thienopyrimidine Derivatives |
|---|---|---|
| Purity | >98% | Higher reactivity than non-chlorinated analogs |
| Melting Point | 218-220°C | Improved thermal stability |
| Solubility | Soluble in DMSO, DMF | Better organic solvent compatibility |
2. Applications & Industrial Uses
Primary applications include:
- Pharmaceutical intermediates for kinase inhibitors
- Agrochemical precursors
- OLED material synthesis
- Cross-coupling reactions in organic chemistry
3. Usage Guidelines
Handling Recommendations:
- Store at 2-8°C in airtight containers
- Use under inert gas atmosphere for sensitive reactions
- Recommended reaction solvents: anhydrous THF or DCM
4. Case Studies
Case 1: Pharmaceutical API Development
Client achieved 92% yield in JAK2 inhibitor synthesis using our compound as key intermediate.
Case 2: Agricultural Chemical Production
Enabled 40% cost reduction in fungicide manufacturing through optimized chlorothienopyrimidine pathway.
5. Client Success Stories
ABC Pharma (Germany):
“4-Chlorothieno[3,2-d]pyrimidine from VIVALR showed consistent >99% HPLC purity across 15 batch productions, accelerating our preclinical development timeline by 6 months.”
ChemFront Co., Ltd (USA):
“The compound’s excellent batch-to-batch consistency improved our Suzuki coupling reaction efficiency by 35% compared to previous suppliers.”
6. Request Custom Quote
Contact our technical team for bulk pricing and custom synthesis options:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Request SDS & COA: Specify batch quantity and required documentation.


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