4-Chlorothieno[3,2-d]pyrimidine

Product Name:4-Chlorothieno[3
2-d]pyrimidine
CAS:16269-66-2
MFC6H3ClN2S
MW:170.62
EINECS:
MOL File:16269-66-2.mol

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Comprehensive Guide to 4-Chlorothieno[3,2-d]pyrimidine

1. Product Overview & Specifications

4-Chlorothieno[3,2-d]pyrimidine (CAS 5390-89-4) is a heterocyclic compound with molecular formula C6H3ClN2S. Key parameters:

Parameter Specification Comparison vs. Thienopyrimidine Derivatives
Purity >98% Higher reactivity than non-chlorinated analogs
Melting Point 218-220°C Improved thermal stability
Solubility Soluble in DMSO, DMF Better organic solvent compatibility

2. Applications & Industrial Uses

Primary applications include:

  • Pharmaceutical intermediates for kinase inhibitors
  • Agrochemical precursors
  • OLED material synthesis
  • Cross-coupling reactions in organic chemistry

3. Usage Guidelines

Handling Recommendations:

  • Store at 2-8°C in airtight containers
  • Use under inert gas atmosphere for sensitive reactions
  • Recommended reaction solvents: anhydrous THF or DCM

4. Case Studies

Case 1: Pharmaceutical API Development
Client achieved 92% yield in JAK2 inhibitor synthesis using our compound as key intermediate.

Case 2: Agricultural Chemical Production
Enabled 40% cost reduction in fungicide manufacturing through optimized chlorothienopyrimidine pathway.

5. Client Success Stories

ABC Pharma (Germany):
“4-Chlorothieno[3,2-d]pyrimidine from VIVALR showed consistent >99% HPLC purity across 15 batch productions, accelerating our preclinical development timeline by 6 months.”

ChemFront Co., Ltd (USA):
“The compound’s excellent batch-to-batch consistency improved our Suzuki coupling reaction efficiency by 35% compared to previous suppliers.”

6. Request Custom Quote

Contact our technical team for bulk pricing and custom synthesis options:

Request SDS & COA: Specify batch quantity and required documentation.

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