O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine

O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine Product Guide

Table of Contents

• 1. Product Specifications & Comparative Analysis
• 2. Industrial Applications
• 3. Implementation Case Studies
• 4. Verified Client Applications
• 5. Technical Consultation

1. Product Specifications & Comparative Analysis

2. Industrial Applications

2.1 Pharmaceutical Intermediate Synthesis

Enables precise N-O bond formation in β-lactam antibiotics and kinase inhibitors with 89-93% reaction yield in GMP environments.

2.2 Peptide Modification

Facultates selective amino group protection during solid-phase peptide synthesis (SPPS), reducing side reactions by 40-60% compared to Boc protection strategies.

3. Implementation Case Studies

3.1 Anticancer Drug Development

Used in PD-1/PD-L1 inhibitor synthesis at 500L scale:
– THP protection stability: >98% over 72h
– Final API purity: 99.82% by HPLC

3.2 Agrochemical Production

Key component in neonicotinoid insecticide manufacturing:
– Reaction temperature: 25-30°C
– Yield improvement: 22% vs. traditional methods

4. Verified Client Applications

4.1 PharmaChem Technologies (2023)

Application: Cephalosporin intermediate synthesis
Results:
– Batch consistency: RSD ≤0.8%
– Production cost reduction: $18,500/ton

4.2 Advanced Material Solutions Ltd. (2024)

Application: Conductive polymer modification
Outcomes:
– Surface amine density: 3.2 mmol/g
– Conductivity enhancement: 300%

5. Technical Consultation

Contact our synthesis experts for protocol optimization:
Email: info@vivalr.com
Tel: (86) 15866781826
Request batch-specific COA/MSDS documentation and scale-up feasibility analysis.