2-Hydroxy-3-methoxypyridine

2-Hydroxy-3-methoxypyridine: Comprehensive Product Guide

Contents

• Product Specifications & Comparative Analysis
• Applications & Industrial Uses
• Operational Guidelines & Best Practices
• Case Studies & Client Implementations
• Inquiry & Technical Support

1. Product Specifications & Comparative Analysis

2. Key Applications & Industrial Implementations

Pharmaceutical Intermediate

Widely used in synthesis of antipsychotic drugs and enzyme inhibitors due to its dual functional groups enabling selective binding.

Coordination Chemistry

Acts as bidentate ligand in transition metal complexes for catalytic applications (e.g., Suzuki-Miyaura cross-coupling reactions).

3. Operational Guidelines

Storage Requirements

Store in airtight containers at 2-8°C under inert atmosphere (N₂ or Ar) to prevent oxidation.

Reaction Optimization

Recommended solvent systems: DMF/DMSO for nucleophilic substitutions, THF for Grignard reactions.

4. Client Implementation Case Studies

Case 1: Pharmaceutical Manufacturer (Germany)

Challenge: Required high-purity intermediate for scale-up production of dopamine D2 receptor antagonists.
Solution: Implemented our GMP-grade 2-Hydroxy-3-methoxypyridine in Buchwald-Hartwig amination steps.
Outcome: Achieved 92% yield with ≤0.5% impurities, meeting EMA regulatory requirements.

Case 2: Catalysis Research Lab (USA)

Challenge: Needed stable ligand for asymmetric hydrogenation of α,β-unsaturated ketones.
Solution: Utilized our compound to synthesize Ru(II)-pyridinol complexes.
Outcome: Achieved 85% enantiomeric excess (ee) in test reactions.

5. Technical Inquiry & Ordering

For batch-specific COA, custom synthesis requests, or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

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