2-Amino-5-fluoropyridine

Product Name:2-Amino-5-fluoropyridine
CAS:21717-96-4
MFC5H5FN2
MW:112.11
EINECS:627-638-8
MOL File:21717-96-4.mol

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2-Amino-5-fluoropyridine: Comprehensive Technical Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter 2-Amino-5-fluoropyridine 2-Amino-4-fluoropyridine 3-Amino-5-fluoropyridine
CAS Number 67515-76-6 67515-75-5 67515-77-7
Molecular Formula C5H5FN2 C5H5FN2 C5H5FN2
Purity Grade ≥99% (HPLC) ≥98% ≥97%
Melting Point 92-94°C 88-90°C 85-87°C
Pharma Applications Kinase Inhibitor Synthesis Antibiotic Intermediates Neurological Agents

2. Industrial Applications & Functional Mechanisms

2.1 Pharmaceutical Intermediate

Key roles in developing:

  • FLT3 kinase inhibitors for leukemia treatment
  • EGFR-targeted anticancer compounds
  • Antiviral prodrug activation components

2.2 Agrochemical Synthesis

Critical for:

  • Systemic insecticide formulations
  • Fungicide resistance management systems
  • Herbicide metabolite development

3. Operational Protocols & Safety Guidelines

3.1 Handling Procedures

  • Storage: Nitrogen atmosphere, -20°C
  • Reaction Compatibility: Avoid strong oxidizers

3.2 Safety Data

  • LD50 (oral, rat): 650 mg/kg
  • Recommended PPE: Chem-resistant gloves, face shield

4. Case Studies: Real-World Implementations

4.1 PharmaTech Inc. – Oncology Drug Development

Application: Synthesized third-generation EGFR inhibitors
Result: Achieved 92% tumor growth inhibition in preclinical models

4.2 AgroGuard Solutions – Next-Gen Insecticides

Application: Developed neonicotinoid alternative
Result: 40% higher pest mortality vs. imidacloprid

5. Procurement Strategy & Vendor Selection

Selection Criteria Technical Requirements
Batch Consistency ≤0.5% impurity variation across batches
Regulatory Compliance EDMF/CEP documentation available

6. Technical Consultation & Custom Synthesis

Contact our chemistry experts:
Email: info@vivalr.com
Tel: (86) 15866781826

Customization Options

  • Isotope-labeled versions (13C, 15N)
  • GMP-grade manufacturing
  • Bulk quantities (100kg+ batches)
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