4-Hydroxy-2-(trifluoromethyl)pyrimidine

Product Name:4-Hydroxy-2-(trifluoromethyl)pyrimidine
CAS:1546-80-1
MFC5H3F3N2O
MW:164.09
EINECS:671-817-3
MOL File:1546-80-1.mol

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4-Hydroxy-2-(trifluoromethyl)pyrimidine: Product Overview

Core Specifications

Parameter Specification Competitor A Competitor B
CAS Number 34494-00-3 Same Same
Purity ≥98% (HPLC) 97% 95%
Storage Temp 2-8°C RT RT

Molecular Properties

Formula: C5H3F3N2O
Molecular Weight: 180.09 g/mol
Appearance: White to off-white crystalline powder

Industrial Applications

Pharmaceutical Intermediates

Critical component in synthesis of:

  • Antiviral agents (HIV/HCV inhibitors)
  • Kinase-targeted oncology drugs
  • Neurological disorder therapeutics

Agrochemical Development

Key building block for:

  • Next-gen fungicides
  • Herbicide resistance modifiers
  • Insect growth regulators

Implementation Scenarios

Case 1: Antiviral Drug Synthesis

Challenge: Low yield in nucleoside analog production
Solution: Optimized coupling reaction using 4-Hydroxy-2-(trifluoromethyl)pyrimidine
Outcome: 62% yield increase with 99.2% purity

Case 2: Crop Protection Formulation

Challenge: Environmental persistence of traditional fungicides
Solution: Developed biodegradable alternative using trifluoromethyl group
Outcome: 40% reduction in soil residual levels

Client Success Stories

ABC Pharmaceuticals (USA)

Project: HCV Protease Inhibitor Development
Usage: 150kg batch production
Results: Achieved Phase III clinical trial material specs

Euro AgroChem (Germany)

Project: Broad-spectrum Fungicide
Usage: 2.8-tonne commercial production
Results: EU regulatory approval obtained 2024

Technical Consultation & Ordering

Our capabilities include:

  • Custom synthesis (gram to tonne scale)
  • GMP-grade production available
  • Regulatory support (REACH, FDA DMF)

Contact our chemical experts:
Email: info@vivalr.com
Phone: (86) 15866781826

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