4,6-Dimethylpyrimidine-5-carboxylic acid

Product Name:4
6-Dimethylpyrimidine-5-carboxylic acid
CAS:157335-93-8
MFC7H8N2O2
MW:152.15
EINECS:
MOL File:157335-93-8.mol

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Comprehensive Guide to 4,6-Dimethylpyrimidine-5-carboxylic Acid

Table of Contents

1. Product Overview & Specifications

Basic Information

Chemical Name: 4,6-Dimethylpyrimidine-5-carboxylic acid
CAS Number: 1074-87-7
Molecular Formula: C7H8N2O2
Molecular Weight: 152.15 g/mol
Appearance: White to off-white crystalline powder

Comparative Analysis

Parameter 4,6-Dimethylpyrimidine-5-carboxylic Acid Pyrimidine-5-carboxylic Acid 5-Methylpyrimidine-2-carboxylic Acid
Molecular Weight 152.15 140.11 154.13
Solubility Moderate in DMSO, Methanol High in Water Low in Polar Solvents
Melting Point 228-232°C 215-218°C 205-210°C
Pharma Applications High Medium Low

2. Key Applications

Pharmaceutical Intermediates

Widely used in synthesizing antiviral agents (e.g., HIV protease inhibitors) due to its ability to form stable hydrogen-bonding networks.

Agrochemical Development

Critical component in next-generation fungicides targeting sterol biosynthesis pathways.

Coordination Chemistry

Effective ligand for transition metal catalysts in asymmetric synthesis reactions.

3. Industry Case Studies

Case 1: Antiviral Drug Development

Client: Top 10 Global Pharma Company
Application: Key intermediate in Phase III HIV integrase inhibitor
Result: 23% yield improvement vs. previous synthesis route
Feedback: “Superior regioselectivity compared to analogues”

Case 2: Agricultural Formulation

Client: EU-based Agrochemical Manufacturer
Application: Core structure in novel strobilurin fungicide
Result: 40% broader spectrum activity against fungal pathogens
Feedback: “Optimal balance between lipophilicity and bioactivity”

Case 3: Catalysis Research

Client: Ivy League University Chemistry Lab
Application: Chiral ligand in nickel-catalyzed cross-couplings
Result: Achieved 95% ee in challenging C-O bond formations
Feedback: “Unparalleled stereo-control in complex systems”

4. Request Customized Solutions

Optimize your synthesis with our technical expertise:
Email: info@vivalr.com
Phone: (86) 15866781826

Why Choose Us?

  • GMP-grade production capabilities
  • Batch-to-batch consistency: >99.5% HPLC purity
  • Custom derivatization services available
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