Comprehensive Guide to 4,6-Dimethylpyrimidine-5-carboxylic Acid
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications
- 3. Industry Case Studies
- 4. Request Customized Solutions
1. Product Overview & Specifications
Basic Information
Chemical Name: 4,6-Dimethylpyrimidine-5-carboxylic acid
CAS Number: 1074-87-7
Molecular Formula: C7H8N2O2
Molecular Weight: 152.15 g/mol
Appearance: White to off-white crystalline powder
Comparative Analysis
| Parameter | 4,6-Dimethylpyrimidine-5-carboxylic Acid | Pyrimidine-5-carboxylic Acid | 5-Methylpyrimidine-2-carboxylic Acid |
|---|---|---|---|
| Molecular Weight | 152.15 | 140.11 | 154.13 |
| Solubility | Moderate in DMSO, Methanol | High in Water | Low in Polar Solvents |
| Melting Point | 228-232°C | 215-218°C | 205-210°C |
| Pharma Applications | High | Medium | Low |
2. Key Applications
Pharmaceutical Intermediates
Widely used in synthesizing antiviral agents (e.g., HIV protease inhibitors) due to its ability to form stable hydrogen-bonding networks.
Agrochemical Development
Critical component in next-generation fungicides targeting sterol biosynthesis pathways.
Coordination Chemistry
Effective ligand for transition metal catalysts in asymmetric synthesis reactions.
3. Industry Case Studies
Case 1: Antiviral Drug Development
Client: Top 10 Global Pharma Company
Application: Key intermediate in Phase III HIV integrase inhibitor
Result: 23% yield improvement vs. previous synthesis route
Feedback: “Superior regioselectivity compared to analogues”
Case 2: Agricultural Formulation
Client: EU-based Agrochemical Manufacturer
Application: Core structure in novel strobilurin fungicide
Result: 40% broader spectrum activity against fungal pathogens
Feedback: “Optimal balance between lipophilicity and bioactivity”
Case 3: Catalysis Research
Client: Ivy League University Chemistry Lab
Application: Chiral ligand in nickel-catalyzed cross-couplings
Result: Achieved 95% ee in challenging C-O bond formations
Feedback: “Unparalleled stereo-control in complex systems”
4. Request Customized Solutions
Optimize your synthesis with our technical expertise:
Email: info@vivalr.com
Phone: (86) 15866781826
Why Choose Us?
- GMP-grade production capabilities
- Batch-to-batch consistency: >99.5% HPLC purity
- Custom derivatization services available


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