Table of Contents
- Product Overview & Specifications
- Key Applications & Industrial Uses
- Usage Guidelines & Safety Protocols
- Industry Case Studies (2-3 Examples)
- Request Customized Quotes/Samples
1. Product Overview & Specifications
Basic Chemical Properties
| Parameter | Specification |
|---|---|
| CAS Number | 1072-98-6 |
| Molecular Formula | C5H4ClNO |
| Molecular Weight | 129.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity (HPLC) | ≥98.5% |
| Melting Point | 148-152°C |
| Solubility | Soluble in DMF, DMSO; slightly soluble in ethanol |
Comparative Analysis
| Feature | 2-Chloro-5-hydroxypyridine | 2-Chloro-3-hydroxypyridine |
|---|---|---|
| Reactivity | High nucleophilic substitution potential | Moderate reactivity |
| Thermal Stability | Stable up to 200°C | Decomposes at 180°C |
| Pharma Compatibility | Preferred for antiviral agents | Used in limited drug syntheses |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediates
Critical building block for:
- Protease inhibitors in HIV treatment
- Kinase inhibitors for oncology drugs
- Neurological disorder therapeutics
Agrochemical Synthesis
- Herbicide metabolites (e.g., pyridine-based weed control agents)
- Fungicide precursors with enhanced systemic activity
3. Usage Guidelines & Safety Protocols
| Parameter | Requirement |
|---|---|
| Storage Conditions | 2-8°C in airtight containers under nitrogen |
| Handling PPE | Chemical-resistant gloves, ANSI Z87.1 goggles |
| First Aid Measures | Eye flush (15 mins), respiratory protection if powdered |
| Waste Disposal | Incinerate at 900°C+ with scrubbers |
4. Industry Case Studies
Case 1: Antiviral Drug Development
Client: European Pharma Company (Confidential)
- Challenge: Low yield (42%) in nucleoside analog synthesis
- Solution: Optimized coupling using 2-Chloro-5-hydroxypyridine
- Result: 78% final yield, reduced side reactions
Case 2: Next-Gen Herbicide
Client: Agrochemical Leader (APAC Region)
- Challenge: Environmental persistence of existing products
- Solution: Biodegradable pyridine derivative development
- Result: 94% degradation within 30 days (OECD 307 compliant)
5. Request Customized Quotes/Samples
Contact our technical team for:
- Bulk pricing (100kg+ orders)
- GMP-grade manufacturing options
- Custom synthesis derivatives
Email: info@vivalr.com
Phone: (86) 15866781826
Why Choose Us?
- ISO 9001:2015 certified production
- 99.7% on-time delivery rate
- 24/7 technical support
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