4-Chloropyridinium Chloride: Technical Guide & Application Handbook
Table of Contents
1. Product Overview & Specifications
| Parameter | 4-Chloropyridinium Chloride | Alternative Reagents |
|---|---|---|
| CAS Number | 20295-53-8 | N/A |
| Molecular Formula | C5H5Cl2N | Varies by compound |
| Purity Grade | ≥98% (HPLC) | Typically 95-97% |
| Storage Conditions | 2-8°C in dry atmosphere | Room temperature (inferior stability) |
2. Key Applications & Industrial Uses
Core Functional Areas:
- Pharmaceutical intermediates synthesis
- Chlorination reactions catalyst
- Organic electronics precursor
- Agrochemical formulation additive
Mechanistic Advantages:
- Superior reaction yields (82-93% vs. 65-75% standard catalysts)
- Reduced side-product formation
- Compatible with polar aprotic solvents
3. Operational Guidelines & Best Practices
Standard Reaction Protocol:
- Charge reactor with substrate (1.0 eq)
- Add 0.15 eq 4-Chloropyridinium chloride
- Maintain temperature at 40-50°C
- Monitor reaction progress via TLC/HPLC
Safety Protocols:
- PPE Requirement: Nitrile gloves, chemical goggles
- Ventilation: Fume hood mandatory
- Spill Management: Absorb with vermiculite
4. Industry Case Studies
Case 1: Pharmaceutical Manufacturer (Basel, Switzerland)
- Challenge: Low yield in antihistamine intermediate synthesis
- Solution: 0.2 mol% 4-Chloropyridinium chloride additive
- Result: Yield increased from 68% → 89%
Case 2: Electronic Materials Supplier (Osaka, Japan)
- Application: OLED precursor synthesis
- Implementation: Solvent-free reaction conditions
- Outcome: 92% purity achieved vs. previous 84%
5. Technical Inquiry & Ordering
Request customized technical support or bulk pricing:
| info@vivalr.com | |
| Phone | (86) 15866781826 |
| Lead Time | 3-5 business days (standard orders) |
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