Product Name:5-Methylpyridin-2-ol
CAS:91914-06-6
MFC6H7NO
MW:109.13
EINECS:200-158-5
MOL File:91914-06-6.mol
Parameter | 5-Methylpyridin-2-ol | Pyridin-2-ol | 3-Methylpyridin-2-ol |
---|---|---|---|
CAS Number | 1003-68-5 | 142-08-5 | 1003-69-6 |
Molecular Formula | C6H7NO | C5H5NO | C6H7NO |
Purity | ≥99% (HPLC) | ≥98% | ≥97% |
Melting Point | 128-131°C | 105-107°C | 118-120°C |
Key Advantages: Enhanced thermal stability vs. analogues, optimal solubility in polar solvents (DMSO, ethanol), and low hygroscopicity.
Challenge: Achieve ≥90% yield in a Suzuki-Miyaura coupling reaction.
Solution: Used 5-Methylpyridin-2-ol (0.5 eq) as co-ligand with Pd(OAc)2.
Result: 93% isolated yield, reduced catalyst loading by 40%.
Challenge: Improve systemic absorption in imidacloprid analogues.
Solution: Incorporated 2% 5-Methylpyridin-2-ol as bioavailability enhancer.
Result: LC50 reduced from 1.2 ppm to 0.45 ppm against aphids.
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Request Quote: Specify required quantity (1kg to ton-scale), purity grade (98%, 99%, HPLC), and application details for optimized recommendations.
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