3-BROMO-2-CHLORO-4-PICOLINE

Product Name:3-BROMO-2-CHLORO-4-PICOLINE
CAS:55404-31-4
MFC6H5BrClN
MW:206.47
EINECS:
MOL File:55404-31-4.mol

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1. Product Information & Specifications

3-Bromo-2-chloro-4-picoline (CAS 55404-31-4) is a halogen-substituted pyridine derivative with molecular formula C6H5BrClN and molecular weight 206.468 g/mol. This specialty chemical exhibits a density of 1.6±0.1 g/cm³ and boiling point of 250.3±35.0°C at standard pressure.

Comparative Analysis

Parameter 3-Bromo-2-chloro-4-picoline 2-Chloro-4-picoline 5-Bromo-2-picoline
Molecular Weight 206.468 127.57 172.02
Boiling Point (°C) 250.3±35.0 194-195 213-215
Density (g/cm³) 1.6±0.1 1.456 1.65

2. Key Applications

  • Pharmaceutical Intermediates: Critical building block for kinase inhibitors and antiviral agents
  • Agrochemical Synthesis: Precursor for herbicides and fungicides
  • Material Science: Ligand in catalytic systems for polymerization
  • Organic Electronics: Charge-transport material in OLED components

3. Industrial Use Cases

3.1 Antiviral Drug Synthesis

Used in Step 3 of Remdesivir analog production via Buchwald-Hartwig amination (Yield: 82%, Purity >99%)

3.2 Herbicide Development

Key intermediate in next-generation ALS inhibitor herbicides showing 95% weed suppression efficacy

4. Client Implementation Scenarios

4.1 Top-tier Pharmaceutical Manufacturer

Annual consumption: 850kg for oncology drug intermediates (2019-2024)

4.2 Agrochemical Leader

Integrated into patent-protected herbicide formula (2022 EU approval)

5. Technical Consultation

For custom synthesis projects or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

Request SDS documentation or synthesis protocols:

  • 24-hour technical response
  • Custom purity grades (98-99.9%)
  • GMP-compliant manufacturing

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