1. Product Overview & Specifications

(2-Amino-pyridin-4-yl)-methanol (CAS: 127170-75-0) is a high-purity heterocyclic compound widely used in pharmaceutical synthesis and organic chemistry research. Key parameters:

2. Key Applications

2.1 Pharmaceutical Intermediate

Used in synthesizing kinase inhibitors and anticancer agents through:

• Pd-catalyzed cross-coupling reactions
• Selective O-methylation processes

2.2 Material Science

Critical component in:

• Metal-organic frameworks (MOFs)
• Photoactive coordination polymers

2.3 Agrochemical Development

Key precursor for:

• Herbicidal pyridine derivatives
• Fungicide intermediates

3. Usage Scenarios

3.1 Anticancer Drug Synthesis

Typical Protocol:

1. Dissolve 5g in anhydrous DMF (50mL)
2. Add 1.2eq K₂CO₃ under N₂ atmosphere
3. Stir at 60°C for 4hrs
4. Yield: 82-85% after purification

3.2 MOF Construction

Optimal conditions:

• Molar ratio 1:1.5 with Zn(NO₃)₂
• Solvothermal synthesis at 120°C
• Surface area: 980-1050 m²/g

4. Client Success Stories

4.1 ABC Pharma (USA)

Challenge: Needed >98% pure intermediate for Phase II clinical trial material
Solution: Custom synthesis with enhanced purification protocol
Result: 99.2% purity achieved, trial initiated 3 weeks ahead of schedule

4.2 XYZ Biotech (Germany)

Challenge: Scaling ligand synthesis from mg to kg scale
Solution: Optimized catalytic system with 30% cost reduction
Result: 92% yield at 5kg batch scale

4.3 ChemInnovate (China)

Challenge: Developing novel fungicide derivatives
Solution: Structure-activity relationship (SAR) study package
Result: 2 lead compounds with EC₅₀ < 10ppm identified

5. Contact for Custom Solutions

For technical specifications sheets, bulk pricing, or custom synthesis requirements:

Email: info@vivalr.com
Phone: (86) 15866781826

Our chemical engineers can provide:

• Custom purity grades (98-99.9%)
• GMP-compliant manufacturing
• Stability studies (ICH guidelines)