5-Methylpyridin-3-amine Technical Guide
Table of Contents
Product Specifications
| Parameter | Value |
|---|---|
| CAS Number | 3430-19-1 |
| Molecular Formula | C6H8N2 |
| Molecular Weight | 108.14 g/mol |
| Synonyms | 3-Amino-5-methylpyridine, 5-Methyl-3-pyridinamine |
| Appearance | Off-white crystalline powder |
Synthesis Methods
Two primary industrial synthesis routes have demonstrated commercial viability:
- Nitro Reduction Method: Starting from 2-bromo-5-nitro-3-methylpyridine, this route achieves approximately 45% yield through catalytic hydrogenation.
- Amination Process: Utilizing 2-amino-3-methyl-5-nitropyridine as precursor, requiring precise temperature control (60-80°C) and palladium-based catalysts.
Industrial Applications
- Pharmaceutical Intermediates: Critical component in kinase inhibitor production
- Agrochemicals: Key building block for novel pesticide formulations
- Coordination Chemistry: Ligand in transition metal catalysts
Implementation Examples
| Application | Client | Result |
|---|---|---|
| Anticancer Drug Intermediate | Top 10 Pharma Company | Improved synthesis yield by 22% |
| Herbicide Formulation | EU Agrochem Leader | Reduced production costs by 18% |
Technical Consultation
Contact our chemical engineering team for:
- Custom synthesis protocols
- Bulk pricing (100kg+ quantities)
- Technical documentation support
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