5-Bromo-2-iodopyrimidine

5-Bromo-2-iodopyrimidine: Comprehensive Product Guide

Contents

• 1. Product Overview & Specifications
• 2. Key Applications
• 3. Usage Guidelines
• 4. Industry Case Studies
• 5. Technical Comparison
• 6. Supplier Inquiry

1. Product Overview & Specifications

CAS Number: 105035-69-6

Molecular Formula: C₄H₂BrIN₂

Molecular Weight: 324.88 g/mol

2. Key Applications

Widely used as:

• Pharmaceutical intermediate for kinase inhibitors
• Cross-coupling reagent in Suzuki-Miyaura reactions
• Building block for anticancer drug development
• Precursor in organic light-emitting diodes (OLEDs)

3. Usage Guidelines

Handling Recommendations:

• Use under nitrogen atmosphere for sensitive reactions
• Optimal reaction temperature: 60-80°C
• Compatible solvents: DMF, THF, DMSO

4. Industry Case Studies

Case 1: Leading Pharma Company (2023)
Developed novel BTK inhibitor using 5-Bromo-2-iodopyrimidine as key intermediate, achieving 92% yield in Buchwald-Hartwig amination.

Case 2: OLED Materials Manufacturer (2024)
Created blue-emitting materials with 18% improved luminescence efficiency through strategic halogen bonding.

5. Technical Comparison

6. Supplier Inquiry

Request custom synthesis or bulk pricing:

Email: info@vivalr.com
Phone: (86) 15866781826

Technical Support Available for:
– Custom halogenation services
– Stability testing reports
– Regulatory documentation