2-Fluoro-5-bromo-3-methylpyridine

Product Name:2-Fluoro-5-bromo-3-methylpyridine
CAS:29312-98-9
MFC6H5BrFN
MW:190.01
EINECS:642-599-7
MOL File:29312-98-9.mol

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2-Fluoro-5-bromo-3-methylpyridine: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

2-Fluoro-5-bromo-3-methylpyridine (CAS: 374633-94-0) is a halogenated pyridine derivative with molecular formula C7H6BrFN. Key parameters:

Parameter Specification
Molecular Weight 220.03 g/mol
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder
Storage 2-8°C in inert atmosphere

2. Applications & Use Cases

Widely used in:

  • Pharmaceutical Intermediates: Key building block for kinase inhibitors and antiviral agents
  • Agrochemicals: Synthesis of novel fungicides and herbicides
  • Material Science: Precursor for OLED electron-transport materials

3. Industry-Specific Case Studies

Case 1: Anticancer Drug Development

A leading biotech company utilized 2-Fluoro-5-bromo-3-methylpyridine as a critical intermediate in synthesizing FGFR inhibitors, achieving 92% yield in Buchwald-Hartwig amination steps.

Case 2: Agricultural Formulation

European agrochemical producer incorporated this compound into next-gen fungicides, demonstrating 40% higher field efficacy against Botrytis cinerea compared to traditional analogs.

4. Technical Parameter Comparison

Derivative Reactivity Thermal Stability Suzuki Coupling Yield
2-F-5-Br-3-MePy High Up to 180°C 85-92%
5-Bromo-3-methylpyridine Moderate ≤150°C 70-78%

5. Client Success Stories

Client A: Tier-1 Pharma Company

Used in continuous flow synthesis of BTK inhibitors, reducing production costs by 35% while maintaining >99.5% chiral purity.

Client B: OLED Manufacturer

Developed high-efficiency electron transport layers showing 18% improvement in device lifetime (LT80) compared to standard materials.

6. Request a Quote or Sample

Contact our technical team for:

  • Custom synthesis options
  • Bulk pricing (5kg+ quantities)
  • Technical documentation (CoA, MSDS)

Email: info@vivalr.com
Phone: (86) 15866781826

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