Comprehensive Guide to 5-Bromo-2,3-Difluoropyridine
Table of Contents
Product Overview & Specifications
5-Bromo-2,3-Difluoropyridine (CAS 124215-64-3) is a halogenated pyridine derivative widely used as a building block in pharmaceutical and agrochemical synthesis.
| Parameter | Specification |
|---|---|
| Molecular Formula | C5H2BrF2N |
| Molecular Weight | 208.98 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Storage | 2-8°C in airtight container |
Key Applications
- Pharmaceutical Intermediate: Synthesis of kinase inhibitors and antiviral agents
- Agrochemicals: Precursor for novel pesticides and herbicides
- Material Science: Building block for liquid crystal materials
Usage Guidelines
- Handle under inert atmosphere (N2 or Ar) to prevent hydrolysis
- Recommended solvent: Anhydrous THF or DMF
- Typical reaction temperature: 0°C to 80°C
- Storage stability: 24 months when properly stored
Case Studies
Case 1: Antiviral Drug Development
Client: European Pharma Co., Ltd.
Application: Synthesis of broad-spectrum antiviral compound
Result: Achieved 92% yield in Buchwald-Hartwig coupling reaction
Case 2: Herbicide Formulation
Client: AgriChem Solutions Inc.
Application: Development of fluorine-containing herbicide
Result: 40% improvement in weed control efficacy vs. non-fluorinated analogs
Comparative Analysis
| Compound | 5-Bromo-2,3-DFP | 2-Bromo-5-FP | 3,5-Dibromopyridine |
|---|---|---|---|
| Reactivity | High | Moderate | Low |
| Solubility | 0.5 g/L (H2O) | 1.2 g/L | 0.3 g/L |
| Price/kg | $1,200 | $950 | $800 |
Contact for Custom Synthesis & Bulk Orders
Email: info@vivalr.com
Phone: (86) 15866781826
Request:
- Custom purity levels (98%-99.9%)
- Bulk pricing (10kg+ orders)
- Technical support for reaction optimization
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