4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate

Product Name:4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate
CAS:65802-56-4
MFC4H7N3O2S
MW:161.18
EINECS:629-168-9
MOL File:65802-56-4.mol

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4-Amino-6-hydroxy-2-mercaptopyrimidine Monohydrate: Comprehensive User Guide

1. Product Overview & Specifications

4-Amino-6-hydroxy-2-mercaptopyrimidine Monohydrate (CAS 1005-64-3) is a heterocyclic organic compound with molecular formula C4H6N4OS·H2O. Key parameters:

Parameter Specification
Molecular Weight 194.19 g/mol
Purity ≥98% (HPLC)
Appearance Yellow crystalline powder
Solubility Soluble in DMSO, sparingly in water

Technical Comparison Table

Feature Standard Grade Pharma Grade
Purity ≥95% ≥99%
Residual Solvents <0.5% <0.1%

2. Key Applications & Use Cases

Widely used in:

  • Pharmaceutical Intermediates: Synthesis of antiviral and anticancer agents
  • Coordination Chemistry: Ligand for metal-organic frameworks (MOFs)
  • Agrochemicals: Precursor for fungicide development

Typical Reaction Workflow

In thiopurine drug synthesis:

  1. Condensation with haloalkanes at 60-80°C
  2. Purification via column chromatography
  3. Lyophilization for final API production

3. Industry Case Studies

Case 1: European Pharma Leader

Client: Top-10 Oncology Drug Manufacturer
Application: Mercaptopurine Analog Synthesis
Outcome: 22% Yield Improvement with 99.2% Purity

Case 2: Asian Agrochemical Giant

Client: USDA-Approved Fungicide Producer
Application: Systemic Crop Protection Agents
Outcome: 15% Cost Reduction in Downstream Formulation

5. Request Customized Solutions

Contact our technical team for:

  • Bulk pricing (50kg+ orders)
  • GMP-grade synthesis protocols
  • Custom purity profiles (98-99.9%)

Email: info@vivalr.com
Phone: (86) 15866781826

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