4-Methylnicotinic Acid: Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Use Cases
- 3. Industry-Specific Case Studies
- 4. Comparative Analysis with Alternatives
- 5. Procurement Guidance
- 6. Contact for Technical Consultation
1. Product Overview & Specifications
| Parameter | 4-Methylnicotinic Acid | Nicotinic Acid | Isonicotinic Acid |
|---|---|---|---|
| CAS Number | 3222-48-8 | 59-67-6 | 1453-58-3 |
| Molecular Formula | C7H7NO2 | C6H5NO2 | C6H5NO2 |
| Purity Grade | ≥99% (Pharma Grade) | ≥98% | |
| Melting Point | 245-248°C | 236°C | 260°C |
| Solubility | Soluble in hot water, ethanol | Water-soluble | Limited solubility |
2. Key Applications & Use Cases
Pharmaceutical Intermediate
Critical precursor for anti-tuberculosis medications like PA-824 analogs. Enables precise methyl group positioning for enhanced drug targeting.
Organic Synthesis
Used in Suzuki coupling reactions to create complex heterocyclic compounds. Preferred for its stability under catalytic conditions.
Agrochemical Development
Key component in novel fungicides targeting Fusarium species. Provides improved leaf adhesion compared to unmodified nicotinic derivatives.
3. Industry-Specific Case Studies
Case Study 1: Antiviral Drug Development
Client: European Pharma Research Consortium
Application: Synthesis of broad-spectrum antiviral candidates
Result: Achieved 22% higher bioavailability compared to nicotinic acid derivatives in preclinical trials
Case Study 2: Advanced Material Synthesis
Client: US Advanced Materials Lab
Application: Ligand for rare-earth metal catalysts
Result: Enabled 15% yield improvement in OLED precursor production
4. Comparative Analysis with Alternatives
| Feature | 4-Methylnicotinic Acid | Nicotinic Acid | Benzoic Acid |
|---|---|---|---|
| Lipophilicity (LogP) | 1.2 | -0.3 | 1.9 |
| Thermal Stability | Excellent (>250°C) | Good | Moderate |
| Metal Chelation Capacity | Strong | Moderate | Weak |
5. Procurement Guidance
Technical Specifications Checklist
- Confirm HPLC purity certification (≥99%)
- Request residual solvent analysis report
- Verify particle size distribution (80-120μm ideal for most syntheses)
6. Contact for Technical Consultation
For formulation optimization support or bulk procurement quotes:
Email: info@vivalr.com
Phone: (86) 15866781826
Available: Mon-Fri 8:00-17:00 GMT+8


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