2-Amino-5-bromo-4-methyl-3-nitropyridine: Technical Guide & Application Solutions
Table of Contents
1. Product Overview & Specifications
1.1 Chemical Profile
2-Amino-5-bromo-4-methyl-3-nitropyridine (CAS 1072651-65-3) is a premium heterocyclic compound with multiple reactive sites, widely utilized in pharmaceutical synthesis and advanced material development.
1.2 Technical Parameters
Parameter | Specification |
---|---|
Molecular Formula | C6H5BrN3O2 |
Molecular Weight | 259.03 g/mol |
Appearance | Yellow crystalline powder |
Purity (HPLC) | ≥98.5% |
Storage Conditions | 2-8°C in airtight container |
2. Key Applications & Industrial Uses
2.1 Pharmaceutical Intermediate
Essential for synthesizing kinase inhibitors and antiviral agents through:
- Palladium-catalyzed cross-coupling reactions
- Nucleophilic aromatic substitution
- Multi-step heterocycle functionalization
2.2 Material Science Applications
- Coordination complexes for OLED materials
- Ligand precursor in catalytic systems
- Building block for conductive polymers
3. Performance Comparison Analysis
Competitor Product | Purity | Thermal Stability | Reactivity Index |
---|---|---|---|
Standard Nitropyridine | 95-97% | Decomposes at 150°C | Medium |
Our Product | ≥98.5% | Stable to 180°C | High |
4. Operational Guidelines & Best Practices
4.1 Handling Protocol
- Use nitrogen atmosphere for moisture-sensitive reactions
- Optimal reaction temperature: 60-80°C
- Recommended solvent systems: DMF/DMSO (polar aprotic)
5. Verified Customer Case Studies
5.1 PharmaTech Solutions (Germany)
- Application: Janus kinase (JAK) inhibitor development
- Result: 40% yield improvement in Suzuki-Miyaura coupling
- Purity Achieved: 99.2% (API intermediate)
5.2 Advanced Material Labs (USA)
- Application: Electron-transport layer synthesis
- Result: 15% efficiency gain in OLED devices
- Device Lifetime: 8,000hrs @ 100cd/m²
6. Consultation & Ordering Information
Contact our technical team for:
- Custom synthesis options
- Bulk pricing (50kg+ quantities)
- MSDS & regulatory documentation
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