1. Product Overview & Specifications

6-Chloro-9-(tetrahydro-2-pyranyl)-purine (CAS 54784-18-6) is a purine derivative widely used in pharmaceutical research, particularly in kinase inhibition studies and nucleoside analog synthesis. Key parameters include:

2. Applications & Use Cases

Key Applications:

• Anticancer Drug Development: Serves as a core scaffold for ATP-competitive kinase inhibitors.
• Antiviral Research: Used in nucleoside analog synthesis targeting viral polymerases.
• Chemical Biology: Probe compound for studying purine-binding proteins.

Typical Workflow:

1. Dissolve in anhydrous DMSO (10 mM stock)
2. Combine with kinase buffer (pH 7.4)
3. Incubate at 25°C for 30 min

3. Client Case Studies

Case 1: PharmaTech Inc. (USA)

Challenge: Required high-purity purine derivatives for CDK9 inhibitor development.
Solution: Used 6-chloro-9-(THP)-purine as starting material
Result: Achieved 92% inhibition at 1 μM concentration

Case 2: BioGen Solutions (Germany)

Challenge: Needed stable intermediates for HCV NS5B polymerase inhibitors.
Solution: Implemented batch synthesis using THP-protected purine
Result: Reduced synthesis steps from 7 to 4

4. Contact for Quotation

Request pricing or technical support:

• Email: info@vivalr.com
• Tel: (86) 15866781826

Custom synthesis and bulk orders available (MOQ: 10g)