Ethyl 4,6-Dichloronicotinate: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Chemical Profile
CAS Number: 37444-65-8
Molecular Formula: C8H5Cl2NO2
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: 2-8°C in airtight container
Comparative Specifications
| Parameter | Our Product | Competitor A | Competitor B |
|---|---|---|---|
| Purity Level | 99.2% | 97.5% | 95.8% |
| Chlorine Content | 32.1% | 31.4% | 30.9% |
2. Key Applications & Use Cases
Primary Industrial Uses
- Pharmaceutical intermediates for antihypertensive drugs
- Agrochemical precursor for novel pesticides
- Cross-coupling reactions in catalytic systems
Functional Advantages
- Superior reactivity in Suzuki-Miyaura couplings
- Enhanced thermal stability (decomposition point: 215°C)
- Low moisture sensitivity (≤0.5% water content)
3. Performance Comparison Analysis
| Reaction Type | Yield with Our Product | Industry Average Yield |
|---|---|---|
| Buchwald-Hartwig Amination | 89% | 82% |
| Ullmann Coupling | 76% | 68% |
4. Industry Application Scenarios
Pharmaceutical Manufacturing
Used in 7-step synthesis of Lorcaserin hydrochloride (Belviq®), achieving 23% overall yield improvement compared to traditional methods.
5. Verified Customer Case Studies
Case Study 1: Top 10 Pharma Company
Challenge: Needed high-purity intermediate for GLP-1 receptor agonist development
Solution: Custom micronized grade (D90 ≤50μm)
Result: Reduced reaction time by 40% in scale-up batches
Case Study 2: Agrochemical Leader
Challenge: Development of chiral fungicide
Solution: Optimized stereochemical purity (99.4% ee)
Result: Achieved 92% biocidal efficacy in field trials
6. Technical Consultation & Quotation
Contact our technical team for:
– Custom synthesis parameters
– Bulk order pricing (100kg+ quantities)
– Regulatory support documentation
Email: info@vivalr.com
Tel: (86) 15866781826
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