2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile

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2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile: Ultimate Guide for Buyers & Researchers

Contents

1. Product Specifications & Technical Parameters

Parameter Specification
CAS Number 374624-77-0
Molecular Formula C6HCl2FN2
Molecular Weight 191.99 g/mol
Appearance White to off-white crystalline powder
Purity (HPLC) ≥98.5%
Melting Point 142-145°C
Storage Conditions 2-8°C in inert atmosphere

2. Industrial Applications & Functional Uses

2.1 Pharmaceutical Intermediate

Critical building block for:

  • Kinase inhibitor development
  • Anticancer drug candidates
  • Antiviral compound synthesis

2.2 Agrochemical Synthesis

Key component in:

  • Next-gen fungicides
  • Herbicide active ingredients
  • Insect growth regulators

3. Performance Comparison with Similar Compounds

Feature 2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile 2-Chloro-5-fluoropyridine 5-Fluoro-2-hydroxypyridine
Reactivity High Moderate Low
Thermal Stability Excellent (>150°C) Good Fair

4. Practical Implementation Examples

4.1 Pharmaceutical Synthesis

Used in 3-step synthesis of SGLT2 inhibitors:

  1. Nucleophilic substitution reaction
  2. Catalytic coupling process
  3. Final purification

5. Verified Customer Implementations

Case 1: PharmaCorp (Diabetes Treatment Development)

  • Challenge: Required high-purity intermediate for clinical trial material
  • Solution: Custom synthesis with 99.2% purity
  • Outcome: Accelerated IND submission by 3 months

Case 2: AgroGrowth Ltd (Fungicide Formulation)

  • Challenge: Stability issues in field trials
  • Solution: Optimized crystalline form delivery
  • Result: 40% efficacy improvement

6. Get Expert Technical Support

Contact our chemistry specialists:

Email: info@vivalr.com
Phone: (86) 15866781826

Request:

  • Custom synthesis protocols
  • Bulk pricing (50kg+ quantities)
  • Regulatory documentation
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