2-Ethoxypyridine: Comprehensive User Guide for Industrial Applications
Table of Contents
1. Product Overview & Specifications
| Parameter | 2-Ethoxypyridine | 2-Methoxypyridine | 2-Chloropyridine |
|---|---|---|---|
| CAS Number | 1450-90-6 | 1628-89-3 | 109-09-1 |
| Molecular Formula | C7H9NO | C6H7NO | C5H4ClN |
| Boiling Point | 202-204°C | 195-197°C | 166-168°C |
| Solubility | Miscible in organic solvents | Partial solubility | Limited solubility |
Key Advantage: Superior thermal stability and solvent compatibility compared to analogs.
2. Key Applications & Industrial Uses
Pharmaceutical Intermediate
Enables synthesis of neuroactive compounds through regioselective etherification reactions.
Agrochemical Production
Critical component in pyrethroid-class pesticide formulations with enhanced bioactivity.
Coordination Chemistry
Effective ligand for transition metal catalysts in cross-coupling reactions (Suzuki, Heck).
3. Operational Guidelines & Best Practices
Handling Protocols
- Store under nitrogen atmosphere at 2-8°C
- Use corrosion-resistant equipment (Hastelloy C-276 recommended)
Reaction Optimization
- Optimal molar ratio: 1:1.2 with Grignard reagents
- Maximum yield achieved at 60-70°C in THF solvent
4. Comparative Analysis with Similar Compounds
| Feature | 2-Ethoxypyridine | Pyridine-2-ol | 2-Aminopyridine |
|---|---|---|---|
| Reaction Yield | 92-95% | 78-82% | 85-88% |
| Byproduct Formation | <3% | 8-12% | 5-7% |
5. Verified Customer Success Stories
Case 1: PharmaCorp Ltd.
Application: Synthesis of novel antidepressant API
Result: 40% reduction in reaction steps vs traditional methods
Case 2: AgroGreen Solutions
Application: Development of biodegradable fungicide
Result: Achieved 99.7% purity in final formulation
6. Technical Support & Inquiry
Contact our chemistry experts for customized solutions:
- Email: info@vivalr.com
- Tel: (86) 15866781826
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