4-Benzylpyridine

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Comprehensive Guide to 4-Benzylpyridine: Applications, Case Studies, and Procurement Insights

Table of Contents

Product Overview & Specifications

Product Name: 4-Benzylpyridine (CAS 2116-65-6)

Molecular Formula: C₁₂H₁₁N

Purity: ≥98% (HPLC)

Appearance: Clear colorless to pale yellow liquid

Parameter 4-Benzylpyridine Similar Compounds
Boiling Point 285-287°C Pyridine: 115°C
Solubility Miscible with organic solvents Limited in water
Applications Pharma intermediates, catalyst Narrower scope

Key Applications of 4-Benzylpyridine

1. Pharmaceutical Synthesis: Critical intermediate in antihistamines and CNS drugs.

2. Catalyst Systems: Ligand in asymmetric catalysis for chiral molecule production.

3. Chemical Research: Building block for N-heterocyclic compound development.

Usage Guidelines & Best Practices

Storage: Keep under inert gas at 2-8°C

Handling: Use PPE including nitrile gloves and vapor respirator

Reaction Optimization: Typical usage 2-5 mol% in catalytic applications

Industry-Specific Case Studies

Case 1: Pharmaceutical Intermediate Scale-Up

– Challenge: Improve yield in antihistamine API synthesis

– Solution: Optimized 4-benzylpyridine stoichiometry (0.8 eq)

– Result: 22% yield increase, 99.2% purity

Case 2: Asymmetric Hydrogenation Catalyst

– Application: Chiral amine production

– Outcome: Achieved 92% ee at 15 bar H₂ pressure

Real Client Success Stories

Client 1: Top-10 Pharma Company (Confidential)

– Usage: Key intermediate in new CNS drug development

– Impact: Reduced synthesis steps from 7 to 4

– Volume: 850kg annual procurement

Client 2: Specialty Chemicals Manufacturer

– Application: Catalyst for agrochemical production

– Result: 18% cost reduction vs. previous catalyst system

Inquiry & Contact Information

For technical specifications, pricing, or samples:

Email: info@vivalr.com

Phone: (86) 15866781826

Request Quote: Include your required quantity, purity grade, and application details.

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