Product Name: 4-Benzylpyridine (CAS 2116-65-6)
Molecular Formula: C₁₂H₁₁N
Purity: ≥98% (HPLC)
Appearance: Clear colorless to pale yellow liquid
| Parameter | 4-Benzylpyridine | Similar Compounds |
|---|---|---|
| Boiling Point | 285-287°C | Pyridine: 115°C |
| Solubility | Miscible with organic solvents | Limited in water |
| Applications | Pharma intermediates, catalyst | Narrower scope |
1. Pharmaceutical Synthesis: Critical intermediate in antihistamines and CNS drugs.
2. Catalyst Systems: Ligand in asymmetric catalysis for chiral molecule production.
3. Chemical Research: Building block for N-heterocyclic compound development.
Storage: Keep under inert gas at 2-8°C
Handling: Use PPE including nitrile gloves and vapor respirator
Reaction Optimization: Typical usage 2-5 mol% in catalytic applications
Case 1: Pharmaceutical Intermediate Scale-Up
- Challenge: Improve yield in antihistamine API synthesis
- Solution: Optimized 4-benzylpyridine stoichiometry (0.8 eq)
- Result: 22% yield increase, 99.2% purity
Case 2: Asymmetric Hydrogenation Catalyst
- Application: Chiral amine production
- Outcome: Achieved 92% ee at 15 bar H₂ pressure
Client 1: Top-10 Pharma Company (Confidential)
- Usage: Key intermediate in new CNS drug development
- Impact: Reduced synthesis steps from 7 to 4
- Volume: 850kg annual procurement
Client 2: Specialty Chemicals Manufacturer
- Application: Catalyst for agrochemical production
- Result: 18% cost reduction vs. previous catalyst system
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Request Quote: Include your required quantity, purity grade, and application details.
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