5-BROMONICOTINOYL CHLORIDE

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5-Bromonicotinoyl Chloride Technical Guide

Table of Contents

  1. Product Specifications & Comparative Analysis
  2. Industrial Applications & Functional Advantages
  3. Operational Protocols & Handling Procedures
  4. Application Case Studies
  5. Client Implementation Examples
  6. Technical Consultation & Procurement

1. Product Specifications & Comparative Analysis

Parameter 5-Bromonicotinoyl Chloride Standard Nicotinoyl Chloride
CAS Number 39620-02-5 1005-85-2
Molecular Formula C6H3NOClBr C6H4NOCl
Molecular Weight 220.45 g/mol 141.55 g/mol
Reactivity Enhanced electrophilicity Standard reactivity

2. Industrial Applications & Functional Advantages

This high-purity organobromine compound serves as critical intermediate in:

  • Pharmaceutical synthesis (kinase inhibitor precursors)
  • Agrochemical production (neonicotinoid derivatives)
  • Ligand development for catalytic systems
  • Functional material modification

3. Operational Protocols & Handling Procedures

Essential safety measures compliant with GB 11984-2024 standards:

  • Storage: Maintain inert atmosphere at 2-8°C
  • Handling: Use dry argon glove boxes
  • Neutralization: 10% sodium bicarbonate solution
  • PPE Requirements: Class C chemical-resistant suits

4. Application Case Studies

4.1 Anticancer Drug Intermediate Synthesis

Demonstrated 92% yield improvement in EGFR inhibitor synthesis through optimized acylation reactions.

4.2 Crop Protection Formulation

Developed weather-resistant insecticide with 40% longer field persistence compared to conventional products.

5. Client Implementation Examples

Client Application Outcome
PharmaTech Solutions BTK inhibitor production Reduced synthesis steps from 8 to 5
AgroShield International Systemic insecticide development 60% reduction in LC50 values

6. Technical Consultation & Procurement

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Direct contact: info@vivalr.com | Tel: (86) 15866781826

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