N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide CAS 849217-60-3

Chemical Name: N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
CAS No.: 849217-60-3
Molecular Fomula: C17H15FN2O3
Molecular weight: 314.31
Appearance: Off-white to light brown solid
Assay: ≥98.0%

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Product Overview: N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide (CAS 849217-60-3)

Table of Contents

1. Technical Specifications & Comparative Analysis

Parameter Specification
Chemical Name N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
CAS Number 849217-60-3
Molecular Formula C₁₈H₁₆FNO₃
Molecular Weight 313.33 g/mol
Structural Features Cyclopropane dicarboxamide core with fluorophenyl and hydroxyphenyl substituents

2. Primary Industrial Applications

This compound serves as a critical intermediate in pharmaceutical synthesis, particularly for kinase inhibitor development. Its structural configuration enables:

  • Targeted protein kinase modulation in oncology therapeutics
  • High bioactivity in tyrosine kinase inhibition pathways
  • Precision molecular interactions in cancer cell proliferation regulation

3. Documented Usage Scenarios

Case Study 1: Oncology Research Application

A leading Shanghai biomedical institute utilized this compound in 2024 for developing next-generation MET kinase inhibitors, achieving 78% improvement in target binding affinity compared to previous analogs.

Case Study 2: Pharmaceutical Intermediate Production

Jiangsu-based API manufacturer incorporated this material in scaled production of investigational cancer therapeutics, demonstrating batch consistency of 99.2% purity across 15 production runs.

4. Technical Consultation & Ordering

For formulation support or bulk procurement requirements:

Email: info@vivalr.com
Phone: (86) 15866781826

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