4-Chloro-6-hydrazinopyrimidine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | 4-Chloro-6-hydrazinopyrimidine | Similar Compounds |
|---|---|---|
| CAS Number | 51421-28-8 | N/A |
| Molecular Formula | C4H4ClN5 | Varies by derivative |
| Purity | ≥98% (HPLC) | Typically 95-97% |
| Solubility | Soluble in DMSO, Methanol | Limited in polar solvents |
2. Key Applications
Pharmaceutical Intermediates
Widely used in synthesis of kinase inhibitors and antiviral agents.
Agrochemical Development
Core component in herbicide and pesticide formulations.
Materials Science
Building block for coordination polymers and OLED materials.
3. Usage Guidelines
Handling Precautions
• Store at 2-8°C in airtight container
• Use nitrile gloves and eye protection
Reaction Optimization
Typical reaction conditions:
– Temperature: 60-80°C
– Solvent: DMF/THF mixture
– Catalyst: Pd/C (5 mol%)
4. Application Case Studies
Anticancer Drug Development
Used in multi-step synthesis of CDK4/6 inhibitor candidates:
- Buchwald-Hartwig amination
- Selective chlorination
- Hydrazine substitution
5. Client Success Stories
| Client | Application | Outcome |
|---|---|---|
| PharmaTech Solutions | JAK3 Inhibitor Development | 30% yield improvement vs traditional routes |
| AgroGuard Ltd. | Next-gen Herbicide | EPA approval achieved in 14 months |
6. Request Consultation
Contact our technical team for:
• Custom synthesis options
• Bulk pricing inquiries
• Regulatory documentation
Email: info@vivalr.com
Tel: (86) 15866781826
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