5-Methylpyridine-3-boronic Acid: Technical Guide & Applications

Table of Contents

1. Product Overview & Specifications

Parameter 5-Methylpyridine-3-boronic Acid Pyridine-3-boronic Acid 4-Methylpyridine-2-boronic Acid
CAS Number 1197196-64-3 150360-46-6 1072940-48-0
Molecular Formula C6H8BNO2 C5H6BNO2 C6H8BNO2
Purity (HPLC) ≥98% ≥95% ≥97%
Storage Temperature 2-8°C (desiccated) Ambient 2-8°C

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate: Critical component in Suzuki-Miyaura cross-couplings for:

  • Kinase inhibitor development (EGFR, ALK targets)
  • Anticancer drug candidates (Phase II/III clinical trials)
  • Antiviral compound synthesis

Material Science:

  • OLED precursor synthesis (electron-transport layers)
  • Coordination polymers for gas storage
  • MOF (Metal-Organic Framework) construction

5. Verified Application Cases

Case 1: Oncology Drug Development

Client: Top 10 Global Pharma Company (Confidential)

  • Application: Third-generation EGFR inhibitor synthesis
  • Scale: 200kg batch production
  • Result: 92% coupling efficiency in flow chemistry system

Case 2: OLED Material Production

Client: Leading Korean Display Manufacturer

  • Application: Electron transport layer precursor
  • Spec Requirement: ≤50ppm metal impurities
  • Outcome: Achieved 99.5% purity with 28ppm residual Pd

6. Technical Inquiry & Ordering

Contact our boron chemistry specialists:

Request:

  • Custom synthesis scaling (100g to 500kg)
  • GMP-grade material options
  • Regulatory documentation support
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