2-Bromopyridine-4-methanol: Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
Key Parameters
| Parameter | Value |
|---|---|
| Chemical Name | 2-Bromopyridine-4-methanol |
| CAS Number | 135707-45-6 |
| Molecular Formula | C6H6BrNO |
| Molecular Weight | 202.03 g/mol |
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
Comparative Analysis
| Feature | 2-Bromopyridine-4-methanol | Similar Derivatives |
|---|---|---|
| Reactivity | High (due to Br and -CH2OH groups) | Moderate (limited functional groups) |
| Solubility | Soluble in DMSO, methanol, chloroform | Limited solubility in polar solvents |
2. Applications of 2-Bromopyridine-4-methanol
Pharmaceutical Intermediates
Used in synthesizing kinase inhibitors and antiviral agents. The bromine atom enables cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
Material Science
Acts as a ligand precursor for metal-organic frameworks (MOFs) and catalysts in asymmetric synthesis.
3. Usage Scenarios & Case Studies
Example 1: Suzuki-Miyaura Coupling
Reaction: 2-Bromopyridine-4-methanol + phenylboronic acid → biaryl derivative (85% yield).
Example 2: Ligand Synthesis
Modified to create chiral ligands for Pd-catalyzed C-N bond formation.
4. Customer Success Stories
Case 1: ABC Pharmaceuticals
Challenge: Required high-purity intermediate for preclinical trials.
Solution: Supplied 99% pure 2-Bromopyridine-4-methanol with customized packaging.
Outcome: Accelerated API synthesis by 30%.
Case 2: XYZ Materials Inc.
Used the compound to develop luminescent MOFs for sensor applications.
5. Request a Quote or Technical Support
Contact us for bulk pricing, SDS, or custom synthesis inquiries:
- Email: info@vivalr.com
- Phone: (86) 15866781826
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