2-Bromopyridine-4-methanol

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2-Bromopyridine-4-methanol: Comprehensive Product Guide

1. Product Overview & Specifications

Key Parameters

Parameter Value
Chemical Name 2-Bromopyridine-4-methanol
CAS Number 135707-45-6
Molecular Formula C6H6BrNO
Molecular Weight 202.03 g/mol
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder

Comparative Analysis

Feature 2-Bromopyridine-4-methanol Similar Derivatives
Reactivity High (due to Br and -CH2OH groups) Moderate (limited functional groups)
Solubility Soluble in DMSO, methanol, chloroform Limited solubility in polar solvents

2. Applications of 2-Bromopyridine-4-methanol

Pharmaceutical Intermediates

Used in synthesizing kinase inhibitors and antiviral agents. The bromine atom enables cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).

Material Science

Acts as a ligand precursor for metal-organic frameworks (MOFs) and catalysts in asymmetric synthesis.

3. Usage Scenarios & Case Studies

Example 1: Suzuki-Miyaura Coupling

Reaction: 2-Bromopyridine-4-methanol + phenylboronic acid → biaryl derivative (85% yield).

Example 2: Ligand Synthesis

Modified to create chiral ligands for Pd-catalyzed C-N bond formation.

4. Customer Success Stories

Case 1: ABC Pharmaceuticals

Challenge: Required high-purity intermediate for preclinical trials.
Solution: Supplied 99% pure 2-Bromopyridine-4-methanol with customized packaging.
Outcome: Accelerated API synthesis by 30%.

Case 2: XYZ Materials Inc.

Used the compound to develop luminescent MOFs for sensor applications.

5. Request a Quote or Technical Support

Contact us for bulk pricing, SDS, or custom synthesis inquiries:

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