3-Chloropyridine

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3-Chloropyridine: Product Overview, Applications, and User Guide

Table of Contents

1. Product Overview & Specifications

3-Chloropyridine (CAS 626-60-8) is a halogenated pyridine derivative widely used in pharmaceuticals, agrochemicals, and organic synthesis. Key parameters:

Parameter Specification
Molecular Formula C5H4ClN
Purity ≥99%
Appearance Colorless to pale yellow liquid
Boiling Point 148-150°C
Density 1.205 g/cm³
Storage 2-8°C in airtight container

2. Key Applications & Industry Uses

Primary industrial applications include:

  • Pharmaceutical Intermediates: Synthesis of antihistamines, antivirals, and CNS drugs
  • Agrochemicals: Production of pyridine-based pesticides and herbicides
  • Chemical Synthesis: Building block for metal complexes and catalyst ligands

3. Technical Comparison with Similar Compounds

Compound Reactivity Stability Typical Use Cases
3-Chloropyridine High Moderate Pharma intermediates
2-Chloropyridine Moderate High Agrochemical synthesis
4-Chloropyridine Low High Research chemicals

4. Usage Scenarios & Best Practices

Typical Reaction Conditions:

  • Nucleophilic substitution: 60-80°C in DMF with K2CO3
  • Catalytic coupling: Pd(OAc)2 catalyst system under inert atmosphere

5. Client Case Studies

Case 1: European Pharma Manufacturer
Challenge: Develop novel H1-antagonist with improved bioavailability
Solution: Used 3-chloropyridine as key intermediate in piperidine derivatization
Outcome: 40% yield improvement vs traditional routes

Case 2: Indian Agrochemical Company
Requirement: Cost-effective synthesis of chloronicotinyl insecticide
Implementation: 3-chloropyridine-based pathway optimization
Results: Production costs reduced by 22% annually

6. Request a Quote or Sample

Contact our technical team for:

  • Custom synthesis options
  • Bulk pricing (25kg+ quantities)
  • Regulatory documentation support

Email: info@vivalr.com
Phone: (86) 15866781826

Why Choose Us?
• ISO 9001-certified production
• Global logistics network
• 24/7 technical support

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