Comprehensive Guide to 5-Bromo-4,6-dichloropyrimidine (CAS 68797-61-5)
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Applications & Industrial Uses
- 3. Operational Guidelines
- 4. Industry Case Studies
- 5. Client Success Stories
- 6. Procurement Consultation
1. Product Specifications & Comparative Analysis
| Parameter | 5-Bromo-4,6-dichloropyrimidine | Analogous Compounds |
|---|---|---|
| CAS Number | 68797-61-5 | 36082-50-5 (structural isomer) |
| Molecular Formula | C4HBrCl2N2 | C4HCl2N2Br |
| Molecular Weight | 227.87 g/mol | 227.87 g/mol |
| Purity Grade | ≥98% (HPLC) | 95-97% (standard) |
| Thermal Stability | Stable below 230°C | Decomposes at 200°C |
2. Applications & Industrial Uses
This heterocyclic compound serves as a crucial building block in:
- Pharmaceutical intermediates for kinase inhibitors
- Agrochemical synthesis (herbicide precursors)
- Organic electronic material development
- Cross-coupling reactions in catalytic processes
3. Operational Guidelines
Handling Protocols:
- Store in inert atmosphere at 2-8°C
- Use corrosion-resistant equipment for processing
- Maintain pH between 6.5-7.5 in aqueous solutions
Reactivity Profile:
- Reacts vigorously with strong oxidizing agents
- Compatible with Suzuki-Miyaura coupling conditions
- Undergoes nucleophilic substitution at C-4 position
4. Industry Case Studies
Case 1: Anticancer Drug Development
A Shanghai-based biotech company utilized this compound as a core structure in tyrosine kinase inhibitor research, achieving 73% yield in lead compound optimization.
Case 2: OLED Material Synthesis
Jiangsu materials laboratory reported enhanced electron mobility (12.3 cm²/V·s) in semiconductor layers using brominated pyrimidine derivatives.
5. Client Success Stories
Client A: Contract Research Organization
Achieved 40% reduction in synthesis steps for antipsychotic API using our compound as a key intermediate (Batch size: 150kg, Purity: 99.2%).
Client B: Academic Research Institute
Published Nature Chemistry paper on novel C-H activation methods using this reagent, citing 89% reaction efficiency.
6. Procurement Consultation
For technical specifications, bulk pricing, or custom synthesis requirements:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Our chemical engineering team provides:
- Regulatory compliance documentation
- Custom purity optimization (98-99.9%)
- GMP-grade manufacturing options


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