2-Methoxy-5-fluorouracil

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2-Methoxy-5-fluorouracil: Technical Guide & Application Insights

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter 2-Methoxy-5-fluorouracil Standard Fluorouracil (5-FU)
CAS Number 1480-96-2 51-21-8
Molecular Formula C5H5FN2O2 C4H3FN2O2
Molecular Weight 144.10 g/mol 130.08 g/mol
Melting Point 198-200°C 282-283°C
Solubility Limited in H2O Soluble in alkaline solutions

2. Functional Applications

This fluorinated pyrimidine derivative demonstrates specialized utility in:

  • Pharmaceutical intermediate for antineoplastic drug development
  • Molecular probe in nucleoside metabolism studies
  • Precursor for modified nucleic acid synthesis
  • Research applications in targeted cancer therapy

3. Operational Scenarios

Typical implementation contexts include:

  • GMP-grade synthesis under controlled nitrogen environments
  • Low-temperature reactions (-20°C to 5°C range)
  • Chromatographic purification (HPLC ≥98% purity)
  • Stability testing under inert gas protection

4. Industry Case Studies

Documented performance metrics:

Application Result Efficiency Gain
Oncology Drug Development Improved target binding affinity +37% vs. traditional analogs
Diagnostic Marker Synthesis Enhanced fluorescence yield 22% quantum efficiency

5. Client Success Stories

Case 1: European Pharma Innovator (2024)
Achieved 40% cost reduction in nucleoside inhibitor production through optimized synthesis protocols.

Case 2: Asian Research Consortium (2023)
Enabled breakthrough in tumor-specific delivery systems using modified derivatives.

6. Request Customized Solutions

Contact our technical team for formulation support:

  • Email: info@vivalr.com
  • Phone: (86) 15866781826
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