3,5-Difluoropyridine-2,6-diamine: Technical Guide & Applications
Table of Contents
1. Product Overview & Specifications
3,5-Difluoropyridine-2,6-diamine (CAS 1261580-92-8) is a fluorinated pyridine derivative with molecular formula C5H6F2N3 and molecular weight 158.12 g/mol. This high-purity intermediate exhibits white to off-white crystalline morphology with ≥98% HPLC purity.
Key Parameters:
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥98% | 95-97% | 97% |
| Water Content | ≤0.5% | ≤1.2% | ≤0.8% |
| Storage Stability | 24 months at 2-8°C | 12 months | 18 months |
2. Key Applications & Use Cases
This fluorinated pyridine derivative serves critical roles in:
- Pharmaceutical Synthesis: Key intermediate for HIV protease inhibitors and kinase-targeted oncology therapeutics
- Agrochemical Development: Building block for novel pesticides with improved fluorinated structures
- Material Science: Precursor for conductive polymers in flexible electronics
Typical Reaction Workflow:
- Nucleophilic aromatic substitution with fluorinating agents
- Catalytic amination under inert atmosphere
- Purification via column chromatography (Hexane:EA = 3:1)
3. Industry Case Studies
Case 1: Antiviral Drug Development
Client: Top 10 Global Pharma Company
Application: Synthesis of next-generation HIV integrase inhibitors
Result: Achieved 92% yield in scale-up production (50kg batch)
Case 2: Agricultural Chemical Innovation
Client: EU-based Agrochemical Leader
Application: Development of systemic fungicides with fluorinated pyridine core
Result: Enhanced bioavailability by 40% compared to non-fluorinated analogs
4. Technical Comparison
| Feature | Our Product | Generic Alternatives |
|---|---|---|
| Fluorine Positional Purity | ≥99.5% | 90-95% |
| Metal Impurities | ≤5 ppm | 15-30 ppm |
| Custom Functionalization | Available | Limited |
5. Request Custom Quote
Our technical team provides:
- Bulk pricing (1kg to ton-scale)
- Regulatory support (REACH, FDA DMF)
- Custom synthesis services
Email: info@vivalr.com
Phone: (86) 15866781826
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