4-Cyano-7-Azaindole: Comprehensive User Guide for Pharmaceutical and Research Applications
Table of Contents
1. Product Overview & Specifications
4-Cyano-7-Azaindole (CAS: Pending verification) is a heterocyclic compound with the molecular formula C8H5N3, featuring a cyano group at the 4-position of the azaindole scaffold. This structural configuration enables unique electronic properties for pharmaceutical intermediates and organic synthesis.
| Parameter | 4-Cyano-7-Azaindole | 4-Chloro-6-Cyano-7-Azaindole | 4-Methoxy-7-Azaindole |
|---|---|---|---|
| Molecular Weight | 143.14 g/mol | 177.59 g/mol | 148.17 g/mol |
| CAS Number | Under validation | 935466-70-9 | 122379-63-9 |
| Key Functional Group | Cyano | Chloro + Cyano | Methoxy |
*Specifications subject to batch-specific analysis. Contact technical support for certified COA.
2. Key Applications
2.1 Pharmaceutical Intermediates
Widely employed in kinase inhibitor development due to its ability to modulate enzyme binding affinity through π-π stacking interactions.
2.2 Material Science
Used in organic semiconductor research for electron-deficient building blocks in OLED architectures.
2.3 Agrochemical Development
Serves as a precursor for novel pesticides targeting insect GABA receptors.
3. Usage Scenarios
3.1 Medicinal Chemistry Protocol
Typical Suzuki coupling reaction conditions:
- Catalyst: Pd(PPh3)4 (5 mol%)
- Solvent: DME/H2O (3:1)
- Temperature: 90°C under N2
- Yield: 68-72% (HPLC purity >95%)
3.2 Handling Recommendations
- Storage: -20°C under argon
- Shelf Life: 24 months when unopened
- Safety: Use NIOSH-approved respirator when handling powder
4. Customer Case Studies
4.1 Shanghai Yuanye Bio-Technology
Application: Synthesized BTK inhibitors for autoimmune disease research
Result: Achieved IC50 = 12 nM in cellular assays
Scale: 50g pilot batch production
4.2 Wuhan Ruhening Biotech
Application: Developed fluorescent probes for protein kinase detection
Result: λem = 498 nm with quantum yield Φ = 0.42
Scale: 10kg commercial production
5. Technical Inquiry
For bulk pricing, custom synthesis, or analytical data:
info@vivalr.com
(86) 15866781826
Request current lead times:
GMP-grade batches typically ship within 4-6 weeks


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