5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid

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5-Bromo-2-(methylthio)pyrimidine-4-carboxylic Acid: Comprehensive Technical Guide

Table of Contents

Product Specifications & Comparative Analysis

Parameter Specification
CAS Number 50593-92-5
Molecular Formula C6H5N2O2SBr
Molecular Weight 249.0851 g/mol
Hazard Classification Acute Oral Toxicity (Category 5), Skin Irritation (Category 2), Eye Damage (Category 2A)

Functional Applications

This heterocyclic compound serves as a critical intermediate in pharmaceutical research, particularly in:

  • Development of kinase inhibitors
  • Synthesis of antiviral agents
  • Construction of targeted cancer therapeutics

Operational Guidelines

Safety Protocols:

  • Utilize PPE including nitrile gloves and safety goggles
  • Implement fume hood ventilation for handling procedures
  • Store at 2-8°C in inert atmosphere

Industry Case Studies

Case 1: Antiviral Drug Development
A Shanghai-based research team successfully employed this compound as a core scaffold in novel protease inhibitors, demonstrating 92% viral replication inhibition in preclinical trials.

Case 2: Oncology Research
University of California researchers utilized the bromine substituent for radio-labeling in tumor-targeting molecules, achieving precise biodistribution in murine models.

Procurement Strategy

Supplier Evaluation Criteria Technical Requirements
Purity Certification ≥98.5% (HPLC)
Batch Consistency ISO 9001:2015 Compliance

Technical Inquiry

For analytical reports or bulk procurement specifications:
Email: info@vivalr.com
Tel: (86) 15866781826

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