1. Product Overview & Specifications

CAS No.: 39856-57-0

Molecular Formula: C₅H₄Br₂N₂

Molecular Weight: 251.91 g/mol

Purity: ≥98% (HPLC)

Storage: 2–8°C, protected from light

Comparative Analysis

2. Key Applications in Pharmaceutical Chemistry

• Intermediate for Kinase Inhibitors: Serves as a core building block in oncology drug candidates targeting tyrosine kinase pathways.
• Antiviral Drug Synthesis: Used in the preparation of nucleotide analogs for hepatitis C and HIV therapeutics.
• Material Science: Facilitates the synthesis of conductive polymers for organic electronics.
• Agrochemical Development: Key precursor for herbicides and fungicides with enhanced bioavailability.

3. Synthesis and Reaction Case Studies

Case 1: Suzuki-Miyaura Cross-Coupling

In a 2024 study, researchers utilized 2,6-Dibromopyridin-3-amine to synthesize bipyridine ligands via Pd-catalyzed coupling, achieving 92% yield under mild conditions (60°C, 12h).

Case 2: Buchwald-Hartwig Amination

A 2023 pharmaceutical project demonstrated efficient C-N bond formation using this compound with aryl chlorides, producing antitumor agents with IC₅₀ values < 50 nM.

4. Industry Client Success Stories

Client A: Top 10 Global Pharma Company

Integrated 2,6-Dibromopyridin-3-amine into their pipeline for a JAK2 inhibitor program, reducing synthesis steps by 40% compared to traditional routes.

Client B: Specialty Chemical Manufacturer

Scaled production of OLED materials using this compound as an electron-transport layer precursor, achieving 99.5% purity at metric ton scale.

5. Contact for Technical Support

For bulk pricing, SDS, or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826