2-CHLOROPYRIMIDINE-5-BORONIC ACID: Ultimate Guide for Researchers & Industrial Buyers
Table of Contents
- 1. Key Specifications & Comparative Analysis
- 2. Industrial & Research Applications
- 3. Operational Implementation Strategies
- 4. Verified Client Success Stories
- 5. Custom Synthesis Inquiry
1. Technical Specifications & Competitive Benchmarking
| Parameter | 2-Chloropyrimidine-5-boronic Acid | 2-Fluoropyrimidine-5-boronic Acid | 5-Bromo-2-chloropyrimidine |
|---|---|---|---|
| CAS Number | 1073354-57-4 | 944401-70-5 | 849368-42-3 |
| Molecular Formula | C4H3BClN2O2 | C4H3BFN2O2 | C4H2BrClN2 |
| Purity Grade | ≥98% (HPLC) | ≥97% | ≥95% |
| Suzuki Reaction Yield | 82-89% | 75-81% | N/A |
2. Advanced Functional Applications
Pharmaceutical Development
- Key intermediate for tyrosine kinase inhibitors
- Building block for antiviral compound synthesis
- Cross-coupling reactions in API production
Material Science Innovations
- Conductive polymer precursor
- OLED electron transport layer component
- Coordination polymer framework construction
3. Operational Protocols & Best Practices
Suzuki-Miyaura Coupling Protocol
- Maintain inert atmosphere (N2/Ar)
- Optimal molar ratio 1:1.2 (boronic acid:halide)
- Recommended catalyst: Pd(PPh3)4 (2 mol%)
Storage & Handling
- Store at 2-8°C under nitrogen
- Desiccate with molecular sieves (3Å)
- Reconstitute in anhydrous THF/DMF
4. Documented Client Implementations
Case 1: Oncology Drug Development
- Client: Swiss Pharma Research Group
- Application: Third-generation BTK inhibitor synthesis
- Result: 78% coupling efficiency achieved
Case 2: Flexible Electronics Manufacturing
- Client: Seoul Display Technologies
- Application: Blue OLED emitter layer fabrication
- Result: 18% EQE improvement
5. Technical & Commercial Consultation
For bulk pricing, custom synthesis, or analytical data:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Request SDS, COA, or stability data:
- Specify required quantities (1g-100kg scale)
- Provide application context for optimal purity recommendation


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