4-(Trifluoromethyl)pyridine-3-carboxamide oxime

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4-(Trifluoromethyl)pyridine-3-carboxamide Oxime: Ultimate Product Guide

Contents

Product Overview & Specifications

Parameter Specification Competitor A Competitor B
CAS Number 202429-64-5 Same Same
Purity ≥98% (HPLC) ≥95% ≥97%
Storage 2-8°C desiccated Ambient 2-8°C
Solubility DMSO, Ethanol DMSO only Methanol

Key Applications

Pharmaceutical Intermediates

Critical precursor in synthesizing kinase inhibitors for oncology therapeutics, particularly effective in EGFR-targeted drug development.

Agrochemical Synthesis

Essential component in next-generation fungicides with enhanced trifluoromethyl group stability against environmental degradation.

Chemical Research

Used as ligand in catalytic asymmetric synthesis (up to 92% enantiomeric excess in recent studies).

Usage Guidelines

Recommended Reaction Conditions

Application Solvent Temperature Yield
Amide Coupling DCM 0-5°C 78-82%
Oxime Formation EtOH/H2O RT 90-95%

Industry Case Studies

Case 1: Antiviral Drug Development

Used as core structure in novel HCV NS5B polymerase inhibitors (Phase II clinical trial data showed 3.2x viral load reduction vs control).

Case 2: Agricultural Formulation

Key component in systemic fungicide demonstrating 98% efficacy against Puccinia striiformis in field trials across 12,000 hectares.

Client Success Stories

PharmaCorp Solutions

Challenge: Needed stable trifluoromethyl precursor for continuous flow synthesis.
Solution: Custom particle size distribution (80-120μm) batches
Result: Achieved 24/7 production with 99.3% API consistency

AgroScience Ltd.

Challenge: Required GLP-compliant batches for EPA submission
Solution: Supplied 35kg with full ICH stability data
Result: Accelerated regulatory approval by 14 months

Request Customized Solutions

Optimize your synthesis with our technical expertise:
• Batch sizes from 10g to 1000kg
• Custom purity profiles (90-99.9%)
• Regulatory support packages
Contact our specialists:
Email: info@vivalr.com
Tel: (86) 15866781826

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