2-Acetylbenzo[b]thiophene: Technical Guide & Application Insights
Table of Contents
1. Key Specifications & Comparative Analysis
| Parameter | 2-Acetylbenzo[b]thiophene | Analogous Compounds |
|---|---|---|
| CAS Number | 22720-75-8 | 75894-07-4 (Benzo(b)thiophene-2-acetic acid) |
| Molecular Formula | C10H8OS | C14H16O3S (Derivative example) |
| Molecular Weight | 176.23 g/mol | 264.34 g/mol (Derivative example) |
2. Functional Applications
Core Applications:
- Pharmaceutical Synthesis: Critical intermediate in production of Zileuton (anti-asthma drug)
- Organic Chemistry Research: Precursor for heterocyclic compound development
- Material Science: Component in specialty polymer formulations
3. Industrial Use Cases
Case Study 1: Pharmaceutical Manufacturing
Key role in Abbott Laboratories’ synthesis process for Zileuton (FDA-approved 1997):
- Conversion rate: ≥98% in optimized conditions
- Reaction pathway: 2-Acetylbenzo(b)thiophene → Oxime intermediate → Final API
4. Client Success Stories
Client A: Specialty Chemical Producer
- Application: High-purity API intermediates
- Outcome: 30% yield improvement through optimized protocols
Client B: Research Institution
- Application: Novel polymer development
- Outcome: Achieved 15% thermal stability enhancement
5. Technical Inquiry
For bulk pricing, SDS documentation, or custom synthesis requirements:
| Contact Method | Details |
|---|---|
| info@vivalr.com | |
| Phone | (86) 15866781826 |


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