2-Amino-4-chloro-6-methylpyrimidine: Technical Guide & Application Insights
Table of Contents
1. Product Overview & Specifications
Basic Parameters
Parameter | Specification |
---|---|
CAS Number | 5600-27-7 |
Molecular Formula | C5H6ClN3 |
Molecular Weight | 143.57 g/mol |
Purity | ≥98% (HPLC) |
Appearance | White to off-white crystalline powder |
Comparative Analysis
Grade | Industrial | Pharmaceutical | Research |
---|---|---|---|
Purity | 95-97% | ≥99% | ≥98% |
Residual Solvents | <0.5% | <0.1% | <0.3% |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediates
Widely used in synthesis of kinase inhibitors and antiviral agents. Demonstrates exceptional reactivity in nucleophilic substitution reactions.
Agrochemical Development
Critical component in fungicide formulations, particularly effective against Botrytis cinerea in crop protection.
Material Science
Enables creation of coordination polymers with thermal stability up to 300°C for specialty coatings.
3. Usage Scenarios & Best Practices
Industrial Synthesis
Typical Reaction: 0.1mol compound + 1.2eq alkylating agent in DMF at 60°C under N2 achieves 82-88% yield.
Lab-scale Purification
Recrystallization recommendation: Ethanol/water (3:1 v/v) with 5°C/min cooling gradient.
4. Verified Customer Case Studies
Case 1: Novo Pharmaceuticals (2023)
Challenge: Scale-up of antiviral intermediate from 10g to 50kg batch
Solution: Optimized catalytic system using our 99.5% grade material
Result: 22% yield improvement vs. competitor products
Case 2: AgroGreen Solutions (2024)
Challenge: Fungicide resistance in vineyard applications
Solution: Formulation containing 15% w/w 2-Amino-4-chloro-6-methylpyrimidine
Result: 94% disease suppression vs. 78% industry benchmark
5. Inquiry & Custom Solutions
Request technical documents or discuss bulk orders:
Email: info@vivalr.com
Tel: (86) 15866781826
Our experts provide:
- Batch-specific COA documentation
- Regulatory support (REACH, FDA DMF)
- Custom particle size distributions (10-200μm)