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Table of Contents
- Product Overview & Specifications
- Key Applications & Industrial Uses
- Operational Guidelines & Safety Protocols
- Industry Application Case Studies
- Contact for Technical Consultation
Product Overview & Specifications
Chemical Profile
| Parameter | Methyl 4,6-Dichloronicotinate | Ethyl 4,6-Dichloronicotinate |
|---|---|---|
| CAS Number | 43120-75-6 | N/A |
| Molecular Formula | C7H5Cl2NO2 | C8H7Cl2NO2 |
| Molecular Weight | 220.03 g/mol | 234.06 g/mol |
| Appearance | White crystalline powder | Off-white solid |
| Melting Point | 72-75°C | 68-71°C |
| Solubility | Methanol: 50 mg/mL DCM: 100 mg/mL |
Ethanol: 40 mg/mL THF: 85 mg/mL |
Quality Specifications
| Parameter | Standard Grade | High-Purity Grade |
|---|---|---|
| Purity (HPLC) | ≥98% | ≥99.5% |
| Water Content | ≤0.5% | ≤0.1% |
| Heavy Metals | ≤10 ppm | ≤5 ppm |
Key Applications & Industrial Uses
Pharmaceutical Intermediates
Essential building block in synthesis of:
- Antiviral agents (HIV protease inhibitors)
- Anticancer compounds (Kinase inhibitors)
- Neuropharmaceutical precursors
Agrochemical Synthesis
- Key component in next-gen herbicides
- Fungicide development
- Plant growth regulator precursors
Advanced Material Production
- Liquid crystal material synthesis
- Organic semiconductor development
- Coordination chemistry applications
Operational Guidelines & Safety Protocols
Handling Requirements
| Parameter | Specification |
|---|---|
| Personal Protection | Nitrile gloves, chemical goggles |
| Ventilation | Fume hood required for handling |
| Storage Temperature | 2-8°C in sealed container |
Reaction Optimization
- Optimal reaction temperature: 40-60°C
- Preferred solvents: DMF, THF
- Catalyst compatibility: Pd(PPh3)4, CuI
Industry Application Case Studies
Case Study 1: Pharmaceutical Development
| Parameter | Details |
|---|---|
| Client | Top 10 Global Pharma Company |
| Challenge | Scale-up of antiviral intermediate |
| Solution | Optimized Buchwald-Hartwig amination |
| Result | 98% yield at 500kg scale |
Case Study 2: Agrochemical Innovation
| Parameter | Details |
|---|---|
| Client | EU-based Crop Science Leader |
| Challenge | Novel herbicide resistance issue |
| Solution | Developed new chloronicotinate derivative |
| Result | Patent filed (WO2021156324A1) |
Contact for Technical Consultation
For formulation support or bulk inquiries:
Email: info@vivalr.com
Tel: (86) 15866781826
Our advantages:
- GMP-compliant production facilities
- Custom synthesis capabilities
- 24/7 technical support team
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