5-Bromo-2,4-dimethoxypyrimidine: Comprehensive Product Guide
Table of Contents
- Product Overview & Specifications
- Applications & Industrial Uses
- Usage Guidelines
- Case Studies
- Client Success Stories
- Contact for Custom Solutions
1. Product Overview & Specifications
5-Bromo-2,4-dimethoxypyrimidine (CAS 5734-64-5) is a halogenated pyrimidine derivative widely used as a key intermediate in pharmaceutical and agrochemical synthesis.
| Parameter | Specification | Comparison with 5-Chloro Analog |
|---|---|---|
| Molecular Formula | C6H7BrN2O2 | Cl vs. Br substitution |
| Molecular Weight | 235.04 g/mol | +34.45 g/mol |
| Purity | ≥98% (HPLC) | Similar purity grade |
| Melting Point | 78-82°C | 5°C lower than chloro analog |
2. Applications & Industrial Uses
Primary applications include:
- Pharmaceutical intermediates for antiviral/anticancer drugs
- Building block for kinase inhibitors
- Agrochemical precursors
- Organic electronic materials
3. Usage Guidelines
Typical Reaction Conditions:
| Reaction Type | Catalyst | Temperature | Yield |
|---|---|---|---|
| Suzuki Coupling | Pd(PPh3)4 | 80°C | 85-92% |
| Buchwald-Hartwig Amination | Xantphos/Pd2(dba)3 | 100°C | 78-85% |
4. Application Case Studies
Case 1: Synthesis of antiviral candidate compound
- Used as coupling partner in palladium-catalyzed reaction
- Achieved 89% yield in scale-up production
5. Client Success Stories
European Pharma Leader (Anonymous):
| Challenge | Solution | Result |
|---|---|---|
| Required high-purity intermediate for Phase III trial | Custom synthesis with >99% purity | Successful API registration |
6. Request Customized Solutions
Contact our technical team for bulk orders or custom synthesis requirements:
- Email: info@vivalr.com
- Phone: (86) 15866781826
【Featured Service】GMP-grade production available for pharmaceutical applications
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