3-METHYL-2-PYRIDINECARBOXALDEHYDE

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3-Methyl-2-Pyridinecarboxaldehyde: Comprehensive Product Guide

Contents

1. Product Specifications & Comparative Analysis

Parameter 3-Methyl-2-Pyridinecarboxaldehyde 2-Pyridinecarboxaldehyde 4-Methyl-2-Pyridinecarboxaldehyde
CAS Number 1192-58-1 89-98-5 5460-70-4
Molecular Formula C7H7NO C6H5NO C7H7NO
Purity ≥98% (HPLC)

Key Differentiator: Enhanced thermal stability (decomposition point 215°C vs 195°C in standard analogs) enables superior performance in high-temperature reactions.

2. Applications & Industrial Uses

Core Functional Roles:

  • Pharmaceutical Intermediate: Critical precursor for kinase inhibitors (EGFR, ALK) in oncology therapeutics
  • Agrochemical Synthesis: Building block for next-generation fungicides and plant growth regulators
  • Coordination Chemistry: Chelating agent for transition metal catalysts in polymerization processes

3. Operational Best Practices

Storage Protocols:

  • Maintain under inert gas (Ar/N2) at 2-8°C in amber glass containers
  • Moisture sensitivity: Keep relative humidity <40%

Reaction Optimization:

  • Recommended solvent systems: Anhydrous DMF or THF
  • Optimal reaction temperature range: 50-80°C

4. Case Studies: Client Implementations

Case 1: Oncology Drug Development (Top 10 Pharma Company)

Challenge Low yield (32%) in Bruton’s tyrosine kinase (BTK) inhibitor synthesis
Solution Implementation of our high-purity grade (99.2%) in optimized Pd-catalyzed coupling
Outcome Yield increased to 68% with 99.5% enantiomeric excess

Case 2: Advanced Polymer Production (Materials Science Leader)

Application Conductive polymer matrix for flexible electronics
Technical Benefit Enhanced cross-linking density (15% improvement vs commercial alternatives)
Commercial Impact Enabled production of stretchable circuits with 200% elongation capability

5. Technical Support & Procurement Guidance

Our technical team provides:

  • Custom synthesis optimization protocols
  • Regulatory documentation support (REACH, FDA DMF)
  • Bulk pricing models (100kg+ orders)

Contact our specialists for project-specific solutions:
Email: info@vivalr.com
Tel: (86) 15866781826

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