DIETHYL(3-PYRIDYL)BORANE

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DIETHYL(3-PYRIDYL)BORANE: Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

Parameter DIETHYL(3-PYRIDYL)BORANE
CAS Number 874285-71-3
Molecular Formula C9H14BN
Molecular Weight 147.03 g/mol
Appearance Colorless to pale yellow liquid
Purity ≥97% (GC)
Storage Conditions 2-8°C under inert atmosphere

2. Key Applications

  • Suzuki-Miyaura Cross-Coupling: Efficient catalyst for aryl-aryl bond formation
  • Pharmaceutical Intermediates: Synthesis of kinase inhibitors and CNS drugs
  • Material Science: Precursor for boron-doped nanomaterials
  • Asymmetric Catalysis: Chiral ligand in enantioselective reactions

3. Usage Guidelines

Consideration Protocol
Handling Use under nitrogen/argon with anhydrous solvents
Reaction Solvents THF, DMF, or toluene recommended
Catalyst Loading 1-5 mol% typical for coupling reactions
Safety GHS05: Corrosive. Use PPE and fume hood

4. Case Studies

Case 1: Pharmaceutical API Synthesis

Client: European CRO (Confidential)
Challenge: Low yield (32%) in brivanib alaninate intermediate synthesis
Solution: Replaced Pd(PPh3)4 with 3 mol% DIETHYL(3-PYRIDYL)BORANE
Result: 89% yield, reduced palladium residue to <0.5 ppm

Case 2: OLED Material Development

Client: Asian Materials Lab
Challenge: Inconsistent hole-transport layer performance
Solution: Used as dopant in carbazole-based matrix
Result: 18% improvement in device lifetime (LT80 @ 1000 cd/m²)

5. Supplier Comparison

Vendor Purity Packaging Lead Time
Vivalr Chemicals ≥99% 1g to 1kg ampules 2 weeks
Vendor B ≥97% 5g minimum 6 weeks
Vendor C ≥95% 100g drums only 8 weeks

6. Inquiry & Technical Support

Contact our chemists for batch-specific COA, custom synthesis, or technical queries:
Email: info@vivalr.com
Tel: (86) 15866781826

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