5-Chloro-2-fluoro-3-methylpyridine: Technical Guide & Application Insights
Table of Contents
1. Product Overview & Specifications
5-Chloro-2-fluoro-3-methylpyridine (CAS: 34584-21-7) is a high-purity heterocyclic compound widely used in pharmaceutical and agrochemical synthesis. Key parameters:
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥99% | ≥97% | ≥95% |
| Packaging | 1kg, 5kg, 25kg | 5kg only | 10kg bulk |
| Storage | 2-8°C, inert atmosphere | Ambient | 2-8°C |
Advantages: Superior stability, batch-to-batch consistency, and custom synthesis options.
2. Key Applications
Pharmaceutical Intermediates
Critical for synthesizing kinase inhibitors and antiviral agents. The fluorine-chlorine substitution pattern enables precise molecular interactions in API development.
Agrochemical Synthesis
Used in next-generation insecticides and fungicides, leveraging its pyridine core for enhanced bioactivity and environmental stability.
3. Usage Scenarios
Scenario 1: Anticancer Drug Synthesis
Used in Step 3 of larotrectinib production via Suzuki-Miyaura cross-coupling (yield: 82-88%).
Scenario 2: Herbicide Intermediate
Key component in fluoropyridine-based herbicides, demonstrating 30% higher field efficacy than chloropyridine analogs.
4. Client Case Studies
Case 1: Top 10 Pharma Company (EU)
Challenge: Required GMP-grade batches for Phase III clinical trials
Solution: Supplied 98kg in 3 months with full regulatory support
Result: Accelerated NDA submission by 6 weeks
Case 2: Agrochemical Leader (USA)
Challenge: Scaling production from lab to 200kg/month
Solution: Customized synthesis route optimization
Result: Achieved 92% yield at commercial scale
5. Request Quotation
Contact our technical team for:
- Custom synthesis requirements
- Bulk pricing (100kg+ orders)
- Regulatory documentation
Email: info@vivalr.com
Phone: (86) 15866781826
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