3-Cyano-2-fluoropyridine

Comprehensive Guide to 3-Cyano-2-fluoropyridine

Table of Contents

• Product Overview & Specifications
• Applications & Industry Uses
• Usage Guidelines
• Case Studies
• Client Success Stories
• Request Customized Solutions

1. Product Overview & Specifications

2. Applications & Industry Uses

Pharmaceutical Intermediates

Key building block for kinase inhibitors and antiviral agents. Enables precise fluorination patterns critical for drug bioavailability.

Agrochemical Synthesis

Essential component in novel pesticide formulations requiring selective fluorination for environmental stability.

Material Science

Used in advanced OLED materials and liquid crystal displays where electronic effects of cyano/fluoro groups enhance performance.

3. Usage Guidelines

Handling Protocols

• Always use nitrogen-purged environments for storage
• Reactivity profile: incompatible with strong oxidizers
• Recommended solvent: anhydrous DMF or THF

Synthetic Pathways

Common derivatization routes:
1. Nucleophilic aromatic substitution with KF
2. Cyanation via Pd-catalyzed cross-coupling
3. Directed ortho-fluorination strategies

4. Case Studies

Pharma API Scale-Up

Challenge: A Top 20 Pharma needed 500kg batch with <99.5% enantiomeric purity for clinical trials.
Solution: Optimized Buchwald-Hartwig amination using our 3-Cyano-2-fluoropyridine as key substrate.
Outcome: Achieved 99.7% purity with 82% yield, accelerating IND submission by 3 months.

Agrochemical Formulation

Challenge: Develop next-gen fungicide with reduced environmental persistence.
Solution: Our compound enabled selective fluorination maintaining efficacy while improving degradation profile.
Result: 40% reduction in soil half-life vs previous formulation.

5. Client Success Stories

EuroPharma Solutions

Project: Development of JAK2 inhibitor
Usage: 150kg over 18 months in lead optimization
Feedback: “Consistent quality and technical support reduced development cycle by 25%”

AgroScience Innovations

Project: Novel strobilurin-class fungicide
Consumption: 2.8 metric tons in pilot production
Testimonial: “Critical partner in achieving EPA approval with improved ecotox profile”

MaterialsTech Co., Ltd.

Application: Electron-transport layer for OLED
Volume: 450kg annual procurement
Outcome: 15% efficiency gain in display prototypes

6. Request Customized Solutions

Contact our technical team for:
• Bulk pricing (50kg+ quantities)
• Custom synthesis (modified derivatives)
• Regulatory support (DMF/CEPI filings)

Email: info@vivalr.com
Phone: (86) 15866781826