Pyrazolo[1,5-a]pyrimidine-3-carboxylic Acid: Comprehensive Product Guide
Table of Contents
- Product Specifications & Comparative Analysis
- Key Applications & Functional Advantages
- Operational Guidelines & Safety Protocols
- Industry Case Studies
- Client Success Stories
- Technical Consultation & Ordering
Product Specifications & Comparative Analysis
| Parameter | Pyrazolo[1,5-a]pyrimidine-3-carboxylic Acid | Alternative Heterocyclic Compounds |
|---|---|---|
| CAS Number | 896333-82-1 | Varies by compound |
| Molecular Formula | C8H5N3O2 | – |
| Purity Grade | ≥98% (HPLC) | Typically 95-97% |
| Solubility | DMSO: 50 mg/mL Methanol: 20 mg/mL |
Limited in polar solvents |
Key Applications & Functional Advantages
Pharmaceutical Development
Critical intermediate for kinase inhibitors (EGFR, ALK) with enhanced bioisosteric properties compared to traditional quinazoline derivatives.
Material Science Applications
Building block for OLED electron-transport materials with improved thermal stability (decomposition point: 285°C vs. 240°C in similar compounds).
Operational Guidelines & Safety Protocols
- Storage: Maintain at 2-8°C under inert atmosphere
- Handling: Use nitrogen-glove box for moisture-sensitive reactions
- Reactivity: Compatible with Suzuki-Miyaura coupling (Pd0 catalysis)
Industry Case Studies
Case 1: Oncology Drug Development
Global Pharma Co. achieved 40% improved binding affinity in third-generation EGFR inhibitors using our GMP-grade material (Batch No. PPCA-2210).
Client Success Stories
Client A: Advanced Materials Research
Electroluminescent efficiency increased from 18% to 22% in prototype OLED devices through our customized purity upgrade program.
Technical Consultation & Ordering
Contact our chemists for:
- Custom synthesis (mg to kg scale)
- Regulatory documentation support
- Bulk pricing (10kg+ orders)
Email: info@vivalr.com
Phone: (86) 15866781826
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