4-Chloro-6-methoxypyrimidine (CAS 1005-02-3) is a heterocyclic aromatic organic compound widely used in pharmaceutical intermediates and agrochemical synthesis. Molecular formula: C5H5ClN2O. Molecular weight: 144.56 g/mol. Appearance: White to off-white crystalline powder.
| Parameter | VIVALR Standard | Supplier A | Supplier B |
|---|---|---|---|
| Purity | ≥99.5% | ≥98.0% | ≥99.0% |
| Melting Point | 112-114°C | 110-113°C | 111-114°C |
| Residual Solvents | <0.1% | <0.5% | <0.3% |
Critical component in synthesis of kinase inhibitors (e.g., EGFR inhibitors) and antiviral agents.
Used in development of pyrimidine-based fungicides and herbicides with enhanced environmental stability.
Building block for liquid crystal materials and organic conductive polymers.
- Store in airtight containers at 2-8°C
- Protect from light and moisture
- Use PPE including chemical goggles and nitrile gloves
- Implement local exhaust ventilation
Typical reaction conditions for nucleophilic substitution: 80-100°C in DMF with K2CO3 as base.
Client: Top 10 Global Pharma Company
Application: Synthesis of third-generation EGFR-TKI inhibitor
Result: Achieved 92% yield in key coupling reaction through optimized purification process
Client: European Agrochemical Producer
Application: Development of systemic fungicide against wheat rust
Result: Improved field efficacy by 40% compared to traditional triazole compounds
Contact our technical team for:
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